PROGRAM. October. Hotel Garden Siena. WIC World Immunotherapy Council
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1 October Hotel Garden Siena PROGRAM Promoted by the NIBIT Foundation in collaboration with the Parker Institute for Cancer Immunotherapy and the World Immunotherapy Council WIC World Immunotherapy Council
2 Thursday October th 25 18:00-20:00 Tuning-up for the THINK TANK: the world-wide I-O voice My I-O story Stefanie Joho (Philadelphia, USA) NIBIT Foundation Michele Maio (Siena, Italy) Parker Institute for Cancer Immunotherapy Ramy Ibrahim (San Francisco, USA) World Immunotherapy Council Bernie Fox (Portland, USA) The Bloomberg Perspective in I-O Asthika Goonewardene (New York Ciy, USA) My I-O story Andrea Bifarini (Terni, Italy) 20:30 Wine & cheese
3 Friday October th 26 08:45-09:00 Welcome addresses Michele Maio (Siena, Italy), Bernie Fox (Portland, USA) and Ramy Ibrahim (San Francisco, USA) SESSION 1 Lung cancer: finding the path ahead Chairs: Luis Paz-Ares (Madrid, Spain), Fouad Namouni (Lawrenceville, USA) and Giovanni Melillo (Washington D.C., USA) 09:00 State of the art - Andrea Ardizzoni (Bologna, Italy) 09:20 Current and perspective challenges Discussant: Luis Paz-Ares (Madrid, Spain) 09:50 The predictive role of TMB - Massimo Barberis (Milan, Italy) 10:05 Combining immuno- and chemo-therapy - Giovanni Melillo (Washington D.C., USA) 10:20 Young investigator idea - Rationale for cancer vaccines design guided by antibody survey - Tyler W. Hulett (Portland, USA) 10:30 Comprehensive Faculty consensus 11:00-11:30 Coffee break SESSION 2 The melanoma immune lesson: past, present, and future Chairs:Alexander M.M. Eggermont (Paris, France), Martin Janek (Bratislava, Slovak Republic) and Pier Giorgio Natali (Rome, Italy) 11:30 State of the art - Anna Maria Di Giacomo (Siena, Italy) 11:50 Current and perspective challenges Discussant: Alexander M.M. Eggermont (Paris, France) 12:20 Microbiota - Maria Rescigno (Milan, Italy) 12:35 Immune contexture - Wolf Hervé Fridman (Paris, France) 12:50 Young investigator idea - TbC 13:00 Comprehensive Faculty consensus 13:30-14:30 Lunch break SESSION 3 Epigenetic immunomodulation: a win-win approach? Chairs: Soldano Ferrone (Boston, USA), Mohammad Azab (Pleasanton, USA) and Elisabetta Ferretti (Rome, Italy) 14:30 State of the art - Michele Maio (Siena, Italy) 14:50 Current and perspective challenges Discussant: Soldano Ferrone (Boston, USA) 15:20 Epigenetics in the melanoma clinic - Alessia Covre (Siena, Italy) 15:35 Genetic basis of tumor antigenicity, recognition and resistance - Drew Pardoll (Baltimora, USA) 15:50 Young investigator idea - NK epigenetics - Chiara Vitale (Genoa, Italy) 16:00 Comprehensive Faculty consensus 16:30-17:00 Tea break SESSION 4 Cancer vaccines: ready again for the prime time? Chairs: Bernie Fox (Portland, USA), Roberto Camerini (Bologna, Italy) and Samir Khleif (Augusta, USA) 17:00 State of the art - Pier Luigi Lollini (Bologna, Italy) 17:20 Current and perspective challenges Discussant: Bernie Fox (Portland, USA) 17:50 Personalized vs shared - Mahesh Yadav (South San Francisco, USA) 18:05 Boosting T cell response to vaccines - Samir Khleif (Augusta, USA) 18:20 Young investigator idea - Neoantigens released by Salmonella-infected tumor cells as a novel vaccine platform - Alessia Melacarne (Milan, Italy) 18:30 Comprehensive Faculty consensus
4 Saturday October th 27 SESSION 5 Big data and data deconvolution Chairs: Nikesh Kotecha (San Francisco, USA), Olivier Provendier (Paris, France) and Dominik Ruettinger (Munich, Germany) 08:30 High level landscape/overview - Chairs 08:40 State of the art: I-O computional science - Zlatko Trajanosky (Innsbruck, Austria) 09:00 Integrative analyses - Nicholas L. Bayless (San Francisco, USA) 09:15 Deep dive talk on analytics for a new technology - Petter Brodin (Stockholm, Sweden) 09:30 Young investigator idea - Data deconvolution - Francesca Finotello (Innsbruck, Austria) 09:40 Current and perspective challenges/comprehensive Faculty Consensus Discussant: Nikesh Kotecha (San Francisco, USA) 10:30-11:00 Coffee break SESSION 6 Learning from existing data: IDO, OX40, HDACi Chairs: Ramy Ibrahim (San Francisco, USA), Patrick Garcia (Aubonne, Switzerland), and Michael Lahn (Geneve, Switzerland) 11:00 State of the art - Kevin Heller (Washington D.C., USA) 11:20 Current and perspective challenges Discussant: Ramy Ibrahim (San Francisco, USA) 11:50 Are we neglecting the biology behind? - Andrea Anichini (Milan, Italy) 12:05 Oncolytic virotherapy: from mono to combo - Graeme Norman V. Hacking (Thousand Oaks, USA) 12:20 Young investigator idea - Cancer testis antigen-based immune cell vaccines - Patrizia Tunici (Siena, Italy) 12:30 Comprehensive Faculty consensus SESSION 7 The III Siena I-O Think Tank 2019 Chairs: Michele Maio (Siena, Italy), Ramy Ibrahim (San Francisco, USA) and Bernie Fox (Portland, USA) 13:00 Shall we refine the formula? Topics for next year? Any other ideas and suggestion? - All 14:00 Lunch THE III THINK TANK A VISION OF I-O: THE SIENA CONSENSUS 2019 OCTOBER 3-5, 2019 HOTEL GARDEN SIENA SEE YOU NEXT YEAR!
5 SCIENTIFIC COMMITTEE Michele Maio - Center for Immuno-Oncology, Siena (Italy) Ramy Ibrahim - Parker Institute for Cancer Immunotherapy, San Francisco (USA) Bernie Fox - Robert W. Franz Cancer Research Center, Earle A. Chiles Research Institute, Portland (USA) George Coukos - University of Lausanne, Lausanne (Switzerland) Jedd D. Wolchok - Memorial Sloan Kettering Cancer Center, New York, USA Axel Hoos - GlaxoSmithKline, Philadelphia (USA) Andrea Anichini - Fondazione IRCCS Istituto Nazionale Tumori, Milan (Italy) Wolf Hervé Fridman - Centre de Recherche des Cordeliers, Paris (France) FACULTY Andrea Anichini - Fondazione IRCCS Istituto Nazionale Tumori, Milan (Italy) Andrea Ardizzoni - Alma Mater Studiorum University of Bologna, Bologna (Italy) Mohammad Azab - Astex Pharmaceuticals, Pleasanton (USA) Massimo Barberis - Istituto Europeo di Oncologia, Milan (Italy) Nicholas L. Bayless - Parker Institute for Cancer Immunotherapy, San Francisco (USA) Andrea Bifarini Terni (Italy) Petter Brodin - Karolinska Institutet, Stockholm (Sweden) Roberto Camerini - Alfasigma, Bologna (Italy) Alessia Covre - Center for Immuno-Oncology, Siena, (Italy) Anna Maria Di Giacomo - Center for Immuno-Oncology, Siena (Italy) Alexander M.M. Eggermont Goustave Roussy, Paris-Sud University, Paris (France) Elisabetta Ferretti - Sapienza University, Rome (Italy) Soldano Ferrone - Harvard Medical School, Boston (USA) Francesca Finotello - Medical University of Innsbruck, Innsbruck (Austria) Bernie Fox - Robert W. Franz Cancer Research Center, Earle A. Chiles Research Institute, Portland (USA) Wolf Hervé Fridman - Centre de Recherche des Cordeliers, Paris (France) Patrick Garcia - Merck KGaA, Aubonne, Canton Vaud (Switzerland) Graeme Norman V. Hacking - Amgen, Thousand Oaks (USA) Kevin Heller - NextCure, Washington D.C. (USA) Tyler W. Hulett - Robert W. Franz Cancer Research Center, Earle A. Chiles Research Institute, Portland (USA) Ramy Ibrahim - Parker Institute for Cancer Immunotherapy, San Francisco (USA) Martin Janek - Merck, Bratislava (Slovak Republic) Stefanie Joho - Philadelphia (USA) Samir Khleif - Georgia Cancer Center, Augusta (USA) Nikesh Kotecha, - Parker Institute for Cancer Immunotherapy, San Francisco (USA) Michael Lahn - Incyte Biosciences International, Geneva (Switzerland) Pier Luigi Lollini - Alma Mater Studiorum University of Bologna, Bologna (Italy) Michele Maio - Center for Immuno-Oncology, Siena, (Italy) Alessia Melacarne - Humanitas University, Milan (Italy) Giovanni Melillo - AstraZeneca, Washington D.C. (USA) Fouad Namouni - Bristol-Myers Squibb, Lawrenceville, (USA) Pier Giorgio Natali - NIBIT Foundation ONLUS, Siena (Italy) Asthika Goonewardene - Bloomberg Intelligence, New York (USA) Drew Pardoll - Johns Hopkins University School of Medicine, Baltimore (USA) Luis Paz-Ares - Hospital Universitario 12 de Octubre, Madrid (Spain) Olivier Provendier - Pierre Fabre Médicament, Paris (France) Maria Rescigno - Humanitas Research Hospital, Milan, (Italy) Dominik Ruettinger - Roche, Munich (Germany) Zlatko Trajanoski - Medical University of Innsbruck, Innsbruck (Austria) Patrizia Tunici - Center for Immuno-Oncology, Siena (Italy) Chiara Vitale - University of Genoa, Genoa, (Italy) Mahesh Yadav - Genentech, South San Francisco (USA) INVITEES FACULTY Gregorio Aversa - Abimmune Technologies, Vancouver (Canada) Marc Ballas - GlaxoSmithKline, Washington D.C. (USA) Catherine Sautès-Fridman - Centre de Recherche des Cordeliers, Paris (France) Michael Imperiale - NEKTAR, San Francisco (USA) Daniela Massi Università degli Studi, Florence (Italy) Paola Nisticò - Regina Elena, National Institute for Cancer Treatment and Research, Rome (Italy) Cosimo Paga - Bristol-Myers Squibb, Rome (Italy) Giuseppe Palmieri - Institute of Biomolecular Chemistry-CNR, Sassari (Italy) Ulrich Pfeffer - San Martino Hospital, National Institute for Cancer Research, Genoa (Italy) Barbara Seliger - Martin Luther Universität Halle-Wittenberg, Halle (Germany)
6 PROMOTED BY ENDORSERS WIC World Immunotherapy Council PLATINUM SPONSOR GOLD SPONSOR SILVER SPONSORS BRONZE SPONSORS A member of the Otsuka group SUPPORTED BY
7 Meeting Venue Hotel Garden Via Custoza, 2 Siena, Italy Scientific Secretariat NIBIT Foundation ONLUS Phone: Fax segreteria@fondazionenibit.org Organizing Secretariat McCann Complete Medical Divisione di VyvaMed Srl Via Spadolini, 7 - Centro Leoni, Palazzo B Milano Phone: Fax
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