International Conference of translational medicine on pathogenesis and therapy of immunomediated diseases.

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1 International Conference of translational medicine on pathogenesis and therapy of immunomediated diseases Innate immunity, inflammation and experimental models of human diseases PRELIMINARY SCIENTIFIC PROGRAM CONFERENCE VENUE Aula Magna Via Festa del Perdono, 7 Milan UNDER THE AUSPICES OF SIICA SECRETARIAT Rita Repizzi Tel siica.amministrazione@siica.it Follow us on FACEBOOK ORGANIZING SECRETARIAT Viale G. Matteotti, Florence Italy Ph siica2019@oic.it OIC Srl is a MedTech Trusted Partner

2 STEERING COMMITTEE Francesco Annunziato Massimo Locati Domenico Mavilio SCIENTIFIC COMMITTEE Francesco Annunziato Flavia Bazzoni Ennio Carbone Marco Cassatella Raffaele De Palma Francesca Di Rosa Armando Gabrielli Francesca Granucci Massimo Locati Enrico Lugli Domenico Mavilio Luis Montaner William Nauseef Luigi Notarangelo Isabella Quinti Angela Santoni Antonio Sica Anna Villa 2

3 THURSDAY, 16 th MAY OPENING CEREMONY - Welcome and Opening Remarks Massimo Locati, University of Milan and Humanitas Research Hospital, Domenico Mavilio, University of Milan and Humanitas Research Hospital, Angela Santoni, La Sapienza University, Rome, Italy SESSION 1 - AUTOINFLAMMATION AND BEYOND Supported by Society of Leukocyte Biology & Journal of Leukocyte Biology Chairs: Ivona Aksientevich, National Institutes of Health, Bethesda, USA William Nauseef, University of Iowa, Iowa City, USA Anna Villa, CNR and San Raffaele Institute, Selected Abstract Ivona Aksientevich, National Institutes of Health, Bethesda, USA Selected Abstract Marco Gattorno, Istituto Giannina Gaslini, Genoa, Italy Selected Abstract Discussion panel Coffee break SESSION 2 - NEW INSIGHTS IN HAEMATOPOIETIC STEM CELL TRANSPLANT Chairs: Marco A. Cassatella, University of Verona, Italy Luca Castagna, Humanitas Research Hospital, TBD CAR T cells and beyond - Clinics Franco Locatelli, Ospedale Bambin Gesù, Rome, Italy HCMV and Viral infection in HSCT (old and new approaches) Didier Blaise, Centre de Recherche en Cancèrologie de Marseille, Marsiglia, France Discussion panel 3

4 THURSDAY, 16 th MAY OPENING KEYNOTE LECTURE Chair: Anna Villa, CNR and San Raffaele Institute, (Re)discovering primary immune deficiencies Luigi Notarangelo, National Institutes of Health, Bethesda, USA Welcome cocktail for all Delegates 4

5 THURSDAY, FRIDAY, 17 th 16 MAY th MAY KEYNOTE LECTURE Chair: Luigi Notarangelo, National Institutes of Health, Bethesda, USA Toward a genetic theory of childhood infectious diseases Jean-Laurent Casanova, Rockfeller University, New York, USA SESSION 3 - IMMUNODEFICIENCIES Chairs: Luigi Notarangelo, National Institutes of Health, Bethesda, USA Anna Villa, CNR and San Raffaele Institute, Title TBD Dan Kastner, National Institutes of Health, Bethesda, USA Selected Abstract Human type I interferonopathies: insights into pathogenesis and therapy Yanick J. Crow, University of Edinburgh, Edinburgh, United Kingdom Selected Abstract Anticytokine autoantibodies: what are they doing and what should we do about it? Steve Holland, National Institutes of Health, Bethesda, USA Selected Abstract Discussion panel Coffee break SATELLITE SYMPOSIUM SPONSORED BY BECTON DICKINSON POSTER VIEW 5

6 FRIDAY, 17 th MAY SESSION 4 - AUTOIMMUNITY Chairs: Francesco Annunziato, University of Florence, Florence, Italy Pierluigi Meroni, Istituto Gaetano Pini, Functional autoantibodiesin systemic sclerosis pathogenesis Armando Gabrielli, University of Ancona, Ancona, Italy Selected Abstract Manipulating regulatory T cell pathways to restore immune tolerance Talal Chatila, Harward University, Boston, USA Selected Abstract Functional adaptation of Foxp3+ regulatory T cells in inflammatory diseases Ciriaco A. Piccirillo, Montreal Diabetes Research Center, Montreal, Quebec, Canada Selected Abstract Discussion panel Coffee break KEYNOTE LECTURE Chair: Angela Santoni, La Sapienza University, Rome, Italy Revisiting interleukin-2: biology and therapeutic advances Abul Abbas, University of California, San Francisco, USA Social Dinner and Award ceremony for the best abstracts 6

7 SATURDAY, 18 th MAY KEYNOTE LECTURE Chair: Domenico Mavilio, University of Milan and Humanitas Research Hospital, Natural killer cells in host defense against viral infection Lewis Lanier, University of California, San Francisco, USA SESSION 5 - IMMUNITY TO INFECTIONS Chairs: Emanuela Marcenaro, University of Genoa, Genoa, Italy Luis Montaner, Wistar Institute, Philadelphia, USA Vaccination, an achievement of civilization Rino Rappuoli, GlaxoSmithKline Vaccines, Siena, Italy Selected Abstract Novel immune-based approaches to cure HIV infection Guido Silvestri, Emory University, Atlanta, USA Selected Abstract A gut feeling: fatal attraction between HIV and Integrin alfa 4 beta 7 Paolo Lusso, National Institutes of Health, Bethesda, USA Selected Abstract Discussion panel Coffee break SATELLITE SYMPOSIUM TBD POSTER VIEW KEYNOTE LECTURE IN MEMORY OF ALESSANDRO MORETTA Chair: Guido Poli, San Raffaele Institute, Innate immunity, inflammation and cancer: double edged swords Alberto Mantovani, Unimed and Humanitas Research Hospital, 7

8 SATURDAY, 18 th MAY SESSION 6 - TUMOR IMMUNOLOGY Chairs: Angela Santoni, La Sapienza University, Rome, Italy Antonio Sica, University of Piemonte Orientale and Humanitas Research Hospital, Deciphering the immune landscape of human cancer microenviroment : Massimiliano Pagani, University of Milan and Istituto Nazionale Genetica Molecolare, Selected Abstract TBD Selected Abstract TBD Discussion panel Coffee break MEMORIAL AND TRIBUTE TO THE MASTERS Chairs: Domenico Mavilio, University of Milan and Humanitas Research Hospital, Milan Angela Santoni, La Sapienza University, Rome, Italy Vito Pistoia: remembered by Lorenzo Moretta Luigi Varesio: remembered by Antonio Sica A friend who perceived the role of tumor microphysiology in antitumor immunity Alessandro Moretta: A wonderful journey in the land of NK cells with an unforgettable friend Franco Locatelli, Ospedale Bambin Gesù, Rome 8

9 SATURDAY, 18 th MAY KEYNOTE LECTURE Chair: Lorenzo Moretta, Ospedale Bambin Gesù, Rome, Italy Innate lymphoid cells: from discovery to cancer treatments Eric Vivier, University of Marseille, Marseille, France FAREWELL Massimo Locati, University of Milan and Humanitas Research Hospital, Domenico Mavilio, University of Milan and Humanitas Research Hospital, 9

International Conference of translational medicine on pathogenesis and therapy of immunomediated diseases

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