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2 18 TH INTERNATIONAL SYMPOSIUM ON INFE Description The aim of this two days symposium is to review current concepts, technology and present advances in infections in the critically ill patients. Sepsis, Pulmonary Infections, Basic Research, Pulmonary Infections Treatment and Prophylaxis Therapy of severe infections will be the topics of the main sessions presented by experts who will review and update the new advances on infections in the critically ill patient. At the end of each session a Clinical Controversy, Pannel Discussion or Case Report Discussion will be organized. Organized by Antonio Artigas, MD Critical Care Center, Sabadell Hospital, University Institute Parc Taulí, Autonomous University of Barcelona, Spain Jean Carlet, MD Direction de l Amélioration de la Qualité et de la Securité des Soins, Paris, France Michael Niederman, MD Division of Pulmonary & Critical Care Medicine, Winthrop University Hospital, Mineola, New York, USA José Garnacho, MD Critical Care Service, Virgen del Rocío Hospital, Sevilla, Spain

3 CTIONS IN THE CRITICALLY ILL PATIENT Advisory Board E. Abraham, MD Birmingham, USA M. Antonelli, MD Rome, Italy E. Bouza, MD Madrid, Spain T. Calandra, MD Lausanne, Switzerland J.Chastre, MD Paris, France J. Cohen, MD Brighton, UK J. Garnacho, MD Sevilla, Spain H. Gerlach, MD Berlin, Germany H. Giamarellou, MD Athens, Greece C. Martin, MD Marseille, France J. Pugin, MD Genève, Switzerland J.A. Paiva, MD Porto, Portugal List of Speakers D. Annane, MD Paris (France) M. Antonelli, MD Rome (Italy) A.Artigas, MD Sabadell (Spain) M. Bassetti, MD Udine (Italy) E. Bouza, MD Madrid (Spain) T. Calandra, MD Lausanne (Switzerland) J. Carlet, MD Paris (France) J. Chastre, MD Paris (France) G. Dimopoulos, MD Athens (Greece) R. Ferrer, MD Sabadell (Spain) J. Garnacho, MD Sevilla (Spain) C. Ince, MD Amsterdam (The Netherlands) M. Kollef, MD S. Louis (USA) C. Martin, MD Marseille (France) I.Martin-Loeches, MD Sabadell (Spain) M. Niederman, MD Mineola (USA) S. Nseir, MD Lille (France) JA. Paiva, MD Porto (Portugal) D. Payen, MD Paris (France P. Póvoa, MD Lisboa (Portugal) J. Pugin, MD Geneve (Switzerland) J. Rodríguez-Baño, MD Sevilla (Spain) M. Schultz, MD Amsterdam (The Netherlands) JL. Teboul, MD Paris (France) JF. Timsitt, MD Grenoble (France) A.Torres, MD Barcelona (Spain) JL. Vincent, MD Brussels (Belgium)

4 18 TH INTERNATIONAL SYMPOSIUM ON INFE Endorsed by * * Las opiniones expresadas por los autores no reflejan necesariamente la posición oficial de la SEIMC.

5 CTIONS IN THE CRITICALLY ILL PATIENT Scientific Program

6 Scientific Program Thursday, 7th February :00-11:00 Satellite Symposium 11:00 Introduction A. Artigas, MD (Sabadell, Spain), J. Carlet, MD (Paris, France) M. Niederman, MD (Mineola, USA), J. Garnacho, MD (Sevilla, Spain) I. SEPSIS Moderators: A. Artigas, MD (Sabadell, Spain) J. Pugin, MD (Genève, Switzerland) 11:10 Literature Review: Sepsis in 2013 JL. Vincent, MD (Brussels, Belgium) 11:40 Corticosteroids and apc in Septic Shock. D. Annane, MD (Paris, France) 12:00-12:20 Coffee-break Antibiotic Therapy in Severe Sepsis: the ABISS Study. R. Ferrer, MD (Terrassa, Barcelona) 12:40 Assessment of Fluid Response. JL. Teboul, MD (Paris, France) 13:00 Type of Fluids in Severe Sepsis. JL. Vincent, MD (Brussels, Belgium) 13:20-14:30 Lunch 14:30 Immunodepresion during Severe Sepsis D.Payen, MD (Paris, France) 14 :50 Immunostimulation as a Strategy in Sepsis J.Pugin, MD (Genève, Switzerland) 15:10 Histone and epigenetics in sepsis T. Calandra, MD (Lausanne, Switzerland) 15:30 Monitoring the Microcirculation C. Ince, MD (Amsterdam, The Netherland) 15:50-16:10 Coffee-break

7 Scientific Program 16:10 Interactive Session: AKI in ICU Moderator: R. Ferrer, MD (Terrassa, Barcelona) Expert Panel: D. Annane, MD (Paris, France), D. Payen, MD (Paris, France), C. Ince, MD Amsterdam, The Netherland) 17:00-19:00 Satellite Symposiums and meetings.

8 Scientific Program FRIDAY, 8th FEBRUARY II. PULMONARY INFECTIONS Moderator: J. Chastre, MD (Paris, France) J. Garnacho, MD (Sevilla, Spain) 08:30 Literature Review: Respiratory Infections M. Niederman, MD (Mineola, USA) 08:50 Inhaled Antibiotics in VAP. J. Chastre, MD (Paris, France) 09:10 Mechanical Devices to Prevent VAP. S. Nseir, MD (Lille, France) 09:30 Prevention Bundles of VAP. M. Antonelli, MD (Rome, Italy) 09:50 How Should We Design the Next Clinical Trials in VAP? M.Kollef, MD (S. Louis, USA) 10:10 Biomarkers and Surveillance Cultures in VAP. P. Póvoa, MD(Lisboa, Portugal) 10:30 Coffee-Break 11:00 VAT vs VAP. I. Martin-Loeches, MD (Sabadell, Spain) 11:20 Do Patients Die From or With VAP? J.F.Timsitt, MD (Grenoble, France) 11:40 Rapid Diagnositc Methods for MDR Pathogens. E. Bouza, MD (Madrid, Spain) 12:10 Breatheomics in Pulmonary Infections M.Schultz, MD (Amsterdam, The Netherlands) 12:30 Debate: Health Care Associated Pneumonia: Is the Concept Useful for Clinical Management? Moderator: A.Torres, MD (Barcelona,Spain) Pro: M. Niederman, MD (Mineola, USA) Con: A.Paiva, MD (Oporto, Portugal) 13:00 Lunch 14:00-15:00 Satellite Symposium.

9 Scientific Program III. TREATMENT AND PROPHYLAXIS Moderators: J. Carlet, MD (Paris, France), A. Paiva, MD (Oporto, Portugal) 15:00 Interactive Session: The Bacterial Peritonitis Moderator: C. Martin, MD (Marseille, France) Expert Panel: G. Dimopoulos, MD(Athens, Greece), M. Antonelli, MD (Rome, Italy), A. Paiva, MD (Oporto, Portugal) 15:45 Epidemiology and Management of Clostridium Difficile in the ICU M.Kollef, MD (S. Louis, USA) 16:05 What Can We Expect from the new Antimicrobials in the Pipeline? M.Bassetti, MD (Udine, Italy) 16:25 Antifungal Therapy and Catheter Management in Candidemia J. Garnacho, MD (Sevilla, Spain) 16:45 Risks Factors and Management of ESBL Enterobacteriaceae J. Rodriguez Baño, MD (Sevilla, Spain) 17:05 Epidemiology and Management of Carbapenemase-producing Klebsiella pneumonia Infections G. Dimopoulos,D (Athens, Greece) 17:25 Invasive Pneumococcal Disease and Vaccines A. Torres, MD (Barcelona, Spain) 17:45 How to Prepare for the Next Pandemics D. Annane, MD(Paris, France) 18:05 Closing Remarks

10 General Information Dates February, 7th, 8th 2013 Symposium Technical Secretariat Josep Irla i Bosch 1-3, entlo Barcelona, Spain Tel Fax info.infections2013@mccann.es Venue Hotel Silken Al-Andalus Palace Avda. de la Palmera, esquina c/paraná Sevilla Tel Fax ESICM SEIMC

11 Registration Form Last Name... First Name... Private address / Institution... Postal Code... City... Country... Telephone... Fax Under the data protection Act 15/99, we inform you that your personal data will be added to the McCann database for promotional and other uses during the Congress. By filling in this application form, you authorize McCann to use your personal data for the mentioned purposes. To exercise your right to access to, rectification and cancellation of this informtion, contact the Congress Secretariat. ESICM SEIMC Please fill this form (type or block capital letters) and mail it or fax it directly to the Symposium Technical Secretariat: Josep Irla i Bosch 1-3, entlo Barcelona, Spain Tel Fax info.infections2013@mccann.es

12 18 TH INTERNATIONAL SYMPOSIUM ON INFECTIONS IN THE CRITICALLY ILL PATIENT Payment TOTAL AMOUNT... I enclose a cheque in Euros payable to McCann Cheque No.... Bank... Cheque amount... Euros Credit card Card No. Cardholder s name... Expiry date Month Year X I autorize McCann to charge the amount of... Euros Cardholder s signature Essential for payment by credit card Cancellation policy Cancellations must be sent in written to the Technical Secretariat. Before January 7 th an administration fee of 30 euros will be debited as management expenses. No fees will be refunded after this date. The participant acknowledges that he/she has no right to lodge damage claims against the organizers should the holding of the Congress be hindered or prevented by unexpected, political or economic events or generally by force majeure, or should the nonappearance of speakers or others reasons necessitate programme changes. With reservation, the participan accepts this proviso.

Preliminary Programme

23 rd INTERNATIONAL SYMPOSIUM ON INFECTIONS IN THE CRITICALLY ILL PATIENT & ICSI Kate Flynn Prize Preliminary Programme DUBLIN 15th-16th FEBRUARY 2018 23 rd INTERNATIONAL SYMPOSIUM ON INFECTIONS IN THE