15 & 16 January International Conference on the Management of Liver Diseases. Organised by Pr Patrick Marcellin

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1 15 & 16 January 2018 PARIS - Palais des Congrès International Conference on the Management of Liver Diseases Organised by Pr Patrick Marcellin Organising Committee Blaise Kutala, Monelle Muntlak Hôpital Beaujon, APHP - INSERM CRI - Université Paris-Diderot APHC Scientific Committee Marc Bourlière, Massimo Colombo, Rafael Esteban, Graham Foster, Michael Fried, Michael Manns, Lawrence Serfaty Follow us on #PHC2018

2 Monday 15 th January INTRODUCTION Liver Diseases: A huge and neglected Public Health burden Patrick Marcellin (France) HEPATITIS C - SESSION 1 Chairs: Michael Manns (Germany), Tarik Asselah (France) Treatment of HCV: 100 % cure? Tarik Asselah (France) 09:00 Difficult to treat patients Stefan Zeuzem (Germany) Results in real life Christophe Hezode (France) 09:30 Round table discussion CLINICAL CASE Management of a patient with HCV related vasculitis Eugene Schiff (USA) K Coffee break HEPATITIS C - SESSION 2 Chairs: Mitchell Shiffman (USA), Marc Bourlière (France) Cost benefit of treatment in F1 patients Graham Foster (UK) Special populations Stanislas Pol (France) The next wave of HCV: The epidemic of intravenous drug use Mitchell Shiffman (USA) Round table discussion STATE OF THE ART LECTURE & AWARD Is global elimination of HCV realistic? Antonio Craxi (Italy) LUNCH WORKSHOPS INDUSTRY SATELLITE SYMPOSIUM NASH SESSION Chairs: Arun Sanyal (USA), Lawrence Serfaty (France) 14:30 Worldwide Epidemiology of NAFLD Stefano Bellentani (Italy) 14:45 Prognosis of NASH Jean-François Dufour (Switzerland) 15:00 Management of a patient with NASH in real life Lawrence Serfaty (France) 15:15 Future therapies in NASH Arun Sanyal (USA) 15:30 Round table discussion CONTROVERSY: DIAGNOSIS OF NASH Chairs: Arun Sanyal (USA), Lawrence Serfaty (France) 15:45 Liver Biopsy Pierre Bedossa (France) 16:00 Indirect markers Laurent Castera (France) K 16:15-16:35 Coffee break AROUND THE WORLD TABLE: ACCESS TO HCV THERAPY WESTERN COUNTRIES OTHER COUNTRIES SPECIAL COMMUNICATION Introduction - Patrick Marcellin (France) Chairs: Massimo Colombo (Italy), Michael Fried (USA) Speakers: Michael Fried (USA), Maria Buti (Spain), Massimo Colombo (Italy), Graham Foster (UK), Victor de Ledinghen (France), Thomas Berg (Germany) Speakers: Mustapha Benazzouz (Morocco), Robert Flisiak (Poland), Vasily Isakov (Russia), Adriana Popescu (Romania), Raymundo Parana (Brazil), Gamal Esmat (Egypt) How to manage liver patients during war Nabil Antaki (Syria) TAKE HOME MESSAGES Marc Bourlière (France) CONCLUSION Patrick Marcellin (France) INDUSTRY SATELLITE SYMPOSIUM

3 Tuesday 16 th January INDUSTRY SATELLITE SYMPOSIUM INTRODUCTION Patrick Marcellin (France) :50 HEPATITIS B - SESSION 1 Chairs: Jidong Jia (China), Georgios Papatheodoridis (Greece) Who and when to treat? Georgios Papatheodoridis (Greece) Is there still a role for interferon? Pietro Lampertico (Italy) Long term safety and efficacy of NUCs Maria Buti (Spain) Round table discussion CONTROVERSY: TO STOP OR NOT TO STOP NUCS? Yes No Chair: Geoffrey Dusheiko (UK) Thomas Berg (Germany) Adrian Gadano (Argentina) K Coffee break HEPATITIS B - SESSION 2 Chairs: Rafael Esteban (Spain), Shiv Sarin (India) New anti-hbv therapies Raymond Schinazi (USA) Delta hepatitis revisited Mario Rizzetto (Italy) How to improve access to therapy for HBV patients? Fabien Zoulim (France) Round table discussion HOW TO CONTROL HBV IN HIGH ENDEMIC REGIONS? Asia Sub-saharian Africa Jidong Jia (China) Lamine Diouf (Senegal) STATE OF THE ART LECTURE The revolution of imagery in liver diseases Valérie Vilgrain (France) LUNCH WORKSHOPS END STAGE LIVER DISEASE AND TRANSPLANTATION Chairs: Richard Moreau (France), François Durand (France) Infections complicating cirrhosis Paolo Angeli (Italy) Allocation of liver grafts worldwide. What is the best system? Pierre-Alain Clavien (Switzerland) How to improve the long-term outcome after liver transplantation François Durand (France) Round table discussion STATE OF THE ART LECTURE Vascular liver diseases: Current management and new concepts HCC SESSION Dominique Valla (France) Chairs: Massimo Colombo (Italy), Didier Samuel (France) Updated 2018 EASL CPGs Peter Galle (Germany) The impact of DAAs on HCC occurence Didier Samuel (France) New approaches in therapy Bruno Sangro (Spain) Round table discussion TAKE HOME MESSAGES Michael Fried (USA) CONCLUSION Patrick Marcellin (France)

4 L U N C H W O R K S H O P S Monday 15 th January How to improve access to treatment in HCV patients Chairs: Graham Foster and Gamal Esmat / Speakers: Victor de Ledinghen and Ahmed El Ray 2- Optimal treatment strategy in HCV patients Chairs: Geoffrey Dusheiko and Adrian Gadano / Speakers: Vincent Leroy and Tarik Asselah 3- Treatment strategy in patients with HIV-HCV co-infection Chairs: Mitchel Shiffman and Stanislas Pol / Speakers: Robert Flisiak and Stéphanie Dominguez 4- Delta hepatitis: current epidemiology and optimized therapy Chairs: Mario Rizzetto and Christian Trepo / Speakers: Raymundo Parana and Dominique Roulot Marullo 5- Optimal management of auto-immune hepatitis Chairs: Michael Manns and Peter Galle / Speakers: Pierre-Emmanuel Rautou and Eleonora de Martin 6- Treatment of HCC in real life Chairs: Peter Ferenci and Olivier Rosmorduc / Speakers: Pierre Nahon and Philippe Merle 7- Optimisation de la prise en charge d un patient avec cirrhose décompensée (French speaking lunch workshop) Chairs: Philippe Mathurin and Christophe Moreno / Speakers: Claire Francoz, Mustapha Benazzouz and Jean-Charles Duclos-Vallée Tuesday 16 th January How to diagnose NASH? Chairs: Arun Sanyal and Pierre Bedossa / Speakers: Ana Carolina Cardoso and Laurent Castera 9- How to manage patients with NASH? Chairs: Lawrence Serfaty and Stefano Bellentani / Speakers: Jérôme Boursier and Raluca Pais 10- Long term benefits and side effects of NUC therapy for HBV. Chairs: Rafael Esteban and Pietro Lampertico / Speakers: Jean-Pierre Bronowicki and Christophe Hézode 11- New therapeutic strategies in HBV patients Chairs: Massimo Levrero and Thomas Berg / Speakers: Philippe Halfon and Maria Buti 12- Liver transplantation issues in 2018 Chairs: Didier Samuel and Pierre-Alain Clavien / Speakers: Dominique Thabut and Sébastien Dharancy 13- Diagnostic et prise en charge d un patient avec NASH Chairs: Daniel Dhumeaux et Jean-François Cadranel / Speakers: Denis Ouzan, Adriana Popescu and Rodolphe Anty

5 FACULTY 2018 Paolo ANGELI Nabil ANTAKI Rodolphe ANTY Tarik ASSELAH Pierre BEDOSSA Stefano BELLENTANI Mustapha BENAZZOUZ Thomas BERG Marc BOURLIERE Jérôme BOURSIER Jean-Pierre BRONOWICKI Maria BUTI Jean-François CADRANEL Ana Carolina CARDOSO Laurent CASTERA Pierre-Alain CLAVIEN Massimo COLOMBO Antonio CRAXI Victor DE LEDINGHEN Eleonora DE MARTIN Sébastien DHARANCY Daniel DHUMEAUX Lamine DIOUF Stéphanie DOMINGUEZ Jean-Charles DUCLOS VALLEE Jean-François DUFOUR François DURAND Geoffrey DUSHEIKO Ahmed EL RAY Gamal ESMAT Rafael ESTEBAN Peter FERENCI Robert FLISIAK Graham FOSTER Claire FRANCOZ Michael FRIED Adrian Carlos GADANO Peter GALLE Philippe HALFON Christophe HEZODE Vasily ISAKOV Jidong JIA Pietro LAMPERTICO Vincent LEROY Massimo LEVRERO Michael MANNS Patrick MARCELLIN Philippe MATHURIN Philippe MERLE Richard MOREAU Christophe MORENO Pierre NAHON Denis OUZAN Raluca PAIS Georgios PAPATHEODORIDIS Raymundo PARANA Stanislas POL Adriana POPESCU Pierre-Emmanuel RAUTOU Mario RIZZETTO Olivier ROSMORDUC Dominique ROULOT MARULLO Didier SAMUEL Bruno SANGRO Arun SANYAL Shiv SARIN Eugene SCHIFF Raymond SCHINAZI Lawrence SERFATY Mitchell SHIFFMAN Dominique THABUT Christian TREPO Dominique VALLA Valérie VILGRAIN Stefan ZEUZEM Fabien ZOULIM

6 INFORMATION CONFERENCE DATES The 11 th Paris Hepatology Conference will be held in Paris, France, from Monday 15 th to Tuesday 16 th January CONFERENCE VENUE The congress will be held at the Paris Congress Center Palais des Congrès located at Porte Maillot, a few minutes walking distance from the Champs Elysées. Address: 2, place de la Porte Maillot Paris France Metro and RER station: Porte Maillot OFFICIAL LANGUAGE The official language of the conference is English. REGISTRATION On-line registration only via the web site: Registration includes access to the scientific sessions, lunches and coffee breaks. ACCOMMODATION C accommodation has negotiated special congress rates. Hotels have been selected for their quality, and location. Reservations have to be made through C accommodation and are subject to availability. To book accommodation, please go to the web site: CME CONTINUOUS MEDICAL EDUCATION ACCREDITATION The 11th Paris Hepatology Conference, Paris, France, 15/01/ /01/2018 has been accredited by the European Accreditation Council for Continuing Medical Education (EACCME ) with 12 European CME credits (ECMEC s). Each medical specialist should claim only those hours of credit that he/she actually spent in the educational activity CONGRESS ADMINISTRATIVE SECRETARIAT Contact: contact@aphc.info PALAIS DES CONGRÈS CONGRESS CENTER Photo Credit by Kiet Thai - SETE - Illuminations Pierre Bideau

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