Cambridge Office & Lab market at tightest levels since early 2000 s.

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MARKETVIEW Cambridge Office/Lab, Q2 2015 Cambridge Office & Lab market at tightest levels since early 2000 s. Office Availability 8.4% Lab Availability 9.6% Occupied Sq. Ft. 22.1 MSF Under Construction 1.7 MSF Figure 1: Office Vacancy vs. Lease Rate Vacancy (%) Lease Rate Per Sq. Ft. ($) 15% $70 $60 10% $50 5% $40 $30 0% $20 Q2 2011 Q3 2011 Q4 2011 Q1 2012 Q2 2012 Q3 2012 Q4 2012 Q1 2013 Q2 2013 Q3 2013 Q4 2013 Q1 2014 Q2 2014 Q3 2014 Q4 2014 Q2 2015 Vacancy Rate 5.0% Average Asking Lease Rate $55.17 OFFICE MARKET As competition for available space in Cambridge has reached a fever pitch, tenants are faced with one of the tightest markets since 2000. Vacancy and availability rates declined to 5.0% and 8.4%, respectively, at the close of Q2 2015. Although rents declined quarter-over-quarter to $55.17 as a direct result of the lackluster quality of remaining availability, they remain up more than 13% year-over-year. Class A office achieved rents that hovered around the mid $70.00 per sq. ft. mark, Q2 2015 CBRE Research 2015 CBRE, Inc. 1

particularly in East Cambridge. The Cambridge office market saw 156,000 sq. ft. of positive absorption in Q2 2015. East Cambridge saw the most activity, posting 133,559 sq. ft. of the market s absorption as vacancy continues to decline, down 40 basis points quarter-over-quarter to 4.1%, its lowest point since mid-2012. What was once considered a peripheral location, Lechmere is now a coveted East Cambridge address, marking the evolution and expansion of the submarket as a core trend throughout the first half of the year. A flurry of activity took place at 2 Canal Park in the second quarter with almost 150,000 sq. ft. of space absorbed. Hubspot, a creator of inbound marketing software, continued to grow its footprint in East Cambridge by executing the largest new office deal of Q2 2015, a 60,000-sq.-ft. expansion. This expansion added to the 117,000 sq. ft. currently occupied at 25 First Street. Philips North America cemented its intent to relocate its North American headquarters to 2 Canal Park as well by inking a deal for 48,000 sq. ft. The consumer electronics company signed a five-year research alliance with MIT and will pump $25 million into innovative research, now from the institute s back yard. Finally, technology security firm Symantec leased 41,000 sq. ft. and will relocate its local operations from Waltham. Other notable transactions included technology giant Hewlett Packard furthering its commitment to West Cambridge by leasing an additional floor at 150 CambridgePark Drive, increasing its occupancy to a total of 73,600 sq. ft. in the building. With tenant demand and the need to be in Cambridge far outpacing available options, particularly in East Cambridge, competition for the remaining blocks of space is fierce. As a result, rapidly escalating rents are expected to continue to climb across all Cambridge submarkets for the foreseeable future. Figure 2: Transactions of Note Tenant Address Sq. Ft. Submarket Type Office MIT 600 Technology Square 105,869 East Cambridge Renewal/Expansion Hubspot 2 Canal Park 60,000 East Cambridge Expansion Philips North America 2 Canal Park 48,000 East Cambridge New Symantec 2 Canal Park 41,000 East Cambridge New Hewlett Packard 150 CambridgePark Drive 29,000 West Cambridge Expansion Lab Bristol-Myers Squibb 100 Binney Street 208,000 East Cambridge New Biogen Idec 301 Binney Street 80,000 East Cambridge Expansion Novartis 45 Sidney Street 48,000 East Cambridge Renewal WaVe Life Sciences 733 Concord Avenue 31,000 West Cambridge New RaNA Therapeutics 200 Sidney Street 24,000 East Cambridge New Q2 2015 CBRE Research 2015 CBRE, Inc. 2

LAB MARKET Much like the office market, and reflecting the general themes throughout Cambridge, the lab market has seen vacancy rates decline to levels unreached since the early 2000s, while tenant demand continues to reach historic highs. Continuing the momentum of the first quarter, the second quarter of 2015 posted almost 392,000 sq. ft. of positive absorption, marking the sixth consecutive quarter of growth. As usual, East Cambridge led the way with a staggering 426,000 sq. ft. of positive absorption. Availability fell 130 basis points quarter-over-quarter to 8.3%, the lowest point in over 15 years. Likewise, vacancy declined by 80 basis points quarter-over-quarter to 6.0%. Average asking rents in the overall Cambridge lab market are also on the rise, up more than $10.00 per sq. ft. NNN quarter-over-quarter to $67.95, almost back to the rent levels in 2000. Putting an exclamation point on the first half of the year, one particular owner is now quoting high $80s NNN for its remaining availability at a new construction lab building, the highest ever asking rent quoted for East Cambridge for lab space. Proving Cambridge to be the North American heart of life science, Bristol-Myers Squibb announced it would open a drug discovery center at 100 Binney Street in Kendall Square. The center will house about 300 employees in 208,000 sq. ft., occupying about half of the Alexandria Center @ Kendall Square building that is slated to open in 2018. In recent years Pfizer, Sanofi SA, Novartis and Baxter International have all consolidated research operations in Cambridge, a trend driven by the unique partnerships with world-class academic institutions and industry leaders. Not to be outdone, Cambridge s home grown darling, Biogen Idec continued its rapid expansion by leasing an additional 80,000 sq. ft. at 301 Binney Street, bringing BioMed s building to full occupancy. Regardless of rents, the minimal availability of lab space in Kendall Square coupled with unwavering demand will leave lab tenants with no choice but to evaluate alternative locations for requirements of all sizes in the back half of the year. Figure 3: Market Statistics Total Cambridge Office/Lab Bldgs Total Sq. Ft. Available (%) Vacant (%) Sublease (%) Quarter Net Absorption YTD Net Absorption Avg Asking Rent $ (NNN) Cambridge Office Cambridge - East 53 7,661,866 7.6 4.1 2.1 133,559 646,731 63.37 Cambridge - Mid 32 1,969,015 5.1 2.3 0.3 (9,515) (9,515) 43.50 Cambridge - West 19 1,932,288 14.7 11.4 1.2 32,231 9,499 37.60 Cambridge Office 104 11,563,169 8.4 5.0 1.7 156,275 646,715 55.17 Cambridge Lab Cambridge - East 69 9,717,745 8.3 6.0 3.3 426,304 586,443 71.45 Cambridge - Mid 7 1,411,672 14.6 0.6 0.0 (58,959) (33,182) 71.26 Cambridge - West 12 656,680 19.0 17.4 0.0 24,596 90,952 46.21 Cambridge Lab 88 11,786,097 9.6 6.0 2.7 391,941 644,213 67.95 Total Cambridge Office/Lab 192 23,349,266 9.0 5.5 2.2 548,216 1,290,928 * The reported numbers for the previous quarter and year have changed due to updated data. Q2 2015 CBRE Research 2015 CBRE, Inc. 3

LAB VACANCY/AVAILABILITY & RENT The Cambridge lab market continues to see rents climb, increasing almost $10.00 per sq. ft. NNN quarter-over-quarter to $67.95 NNN per sq. ft. Availability continued to steadily decline in the second quarter, down 80 basis points quarter-overquarter to 9.6%. Similarly, vacancy also declined by 90 basis points quarter-over-quarter to 6.0%. Leading the way was the East Cambridge lab market, which saw availability and vacancy plummet 130 and 80 basis points quarter-overquarter, respectively. Figure 4: Lab Vacancy/Availability & Rent Vacancy 6.0% Availability 9.6% Lease Rate $67.95 NNN Lease Rate Per Sq. Ft. ($) Vacancy/Availability (%) $70 23% 21% $65 19% $60 17% 15% $55 13% $50 11% 9% $45 7% $40 5% Q2 2013 Q3 2013 Q4 2013 Q1 2014 Q2 2014 Q3 2014 Q4 2014 OFFICE VACANCY/AVAILABILITY & RENT Figure 5: Office Vacancy/Availability & Rent Cambridge office vacancy continues its decline, down 20 basis points quarter-over-quarter to 5.0%, its lowest point since the early 2000s. Similarly, the availability rate declined slightly in the second quarter, down 30 basis points quarterover-quarter to 8.4%. Average asking rents declined for the first time in recent quarters, a direct result of the lack of quality of availability, ending the second quarter at $55.17. Vacancy 5.0% Availability 8.4% Lease Rate $55.17 Gross Lease Rate Per Sq. Ft. ($) Vacancy/Availability (%) $70 20% $60 16% $50 12% $40 8% $30 $20 4% $10 0% Q2 2013 Q3 2013 Q4 2013 Q1 2014 Q2 2014 Q3 2014 Q4 2014 Q2 2015 Q2 2015 CBRE Research 2015 CBRE, Inc. 4

Definitions AVERAGE ASKING LEASE RATE Rate determined by multiplying the asking gross lease rate for each building by its available space, summing the products, then dividing by the sum of the available space with net leases for all buildings in the summary. GROSS LEASES Includes all lease types whereby the tenant pays an agreed rent plus estimated average monthly costs of the operating expenses and taxes for the property, including utilities, insurance and/or maintenance expenses. MARKET COVERAGE Includes all competitive buildings in CBRE s survey set. NET ABSORPTION The change in occupied sq. ft. from one period to the next, as measured by available sq. ft. NET RENTABLE AREA The gross building square footage minus the elevator core, flues, pipe shafts, vertical ducts, balconies and stairwell areas. OCCUPIED AREA (SQ. FT.) Building area not considered vacant. UNDER CONSTRUCTION Buildings that have begun construction as evidenced by site excavation or foundation work. AVAILABLE AREA (SQ. FT.) Available building area that is either physically vacant or occupied. AVAILABILITY RATE Available sq. ft. divided by the net rentable area. VACANT AREA (SQ. FT.) Existing building area that is physically vacant or immediately available. VACANCY RATE Vacant building feet divided by the net rentable area. NORMALIZATION Due to a reclassification of the market, the base, number and square footage of buildings of previous quarters have been adjusted to match the current base. Availability and vacancy figures for those buildings have been adjusted in previous quarters. Cambridge, Massachusetts Photo by istockphoto, www.istockphoto.com Q2 2015 CBRE Research 2015 CBRE, Inc. 5

CONTACTS CBRE OFFICES Suzanne Duca Director of Research +1 617 912 7041 suzanne.duca@cbre-ne.com CBRE/New England 33 Arch Street, 28th Floor Boston, MA 02110 To learn more about CBRE Research, or to access additional research reports, please visit the Global Research Gateway at www.cbre.com/researchgateway. Disclaimer: Information contained herein, including projections, has been obtained from sources believed to be reliable. While we do not doubt its accuracy, we have not verified it and make no guarantee, warranty or representation about it. It is your responsibility to confirm independently its accuracy and completeness. This information is presented exclusively for use by CBRE clients and professionals and all rights to the material are reserved and cannot be reproduced without prior written permission of CBRE.