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Cambridge Office/Lab MarketView CBRE Global Research and Consulting U.S. UNEMPLOYMENT 6.7% MA UNEMPLOYMENT 6.3% OCCUPIED SQ. FT. 19.4M OFFICE AVAIL. 10.0% LAB AVAIL. 18.4% UNDER CONSTRUCTION 1.8MSF *Arrows indicate change from previous quarter. STRONG ECONOMICS INDICATES CAMBRIDGE EXPANSION Quick Stats (Office) Current Y-o-Y Q-o-Q Office Vacancy 7.1% Lease Rate (Gross) $42.62 Hot Topics (Office) 44,438 sq. ft. Only three large block options are available for tenants in the market seeking office space 30,000 sq. ft. and above. Rockwood Capital and The Beal Companies sold One Kendall Square to DivcoWest for $395 million ($589 per sq. ft.). Office Market The Cambridge Office market experienced 44,000 sq. ft. of positive net absorption in the first quarter. The vacancy rate increased by 80 basis points (bps) to 7.1% with the availability rate decreasing by 30 bps to 10%, a statistic that emphasizes limited movement in an extremely tight market. Average asking rents are down $0.70 per sq. ft. from last quarter as more of the top-tier availabilities in the market have been absorbed. Due to limited availability, the Cambridge Office market managed only moderate leasing activity in the first quarter of 2014 with a mix of both renewals and expansions. Leading the way was VMware s renewal at 5 Cambridge Center for 70,000 sq. ft. Existing tenants expanded their current Cambridge footprints in a significant way in the first quarter including InsightSquared, a developer of business analytics software, which grew its footprint by 10,000 sq. ft. by signing a lease at 160 Second Street for 15,000 sq. ft. Leaf, a developer of mobile POS solutions, also expanded by 10,000 sq. ft., signing a sublease at 215 First Street for a total occupancy of 15,000 sq. ft. GoDaddy.com expanded through acquisition by buying local startup Locu, and subsequently signed a 10,000 sq. ft. lease at One Main Street. New demand from technology start-up companies was spread evenly through all Cambridge submarkets in the first quarter. Kensho, a cloud-based technology with funding for an intelligent research assistant, leased 6,000 sq. ft. in mid-cambridge at 17 Dunster Street. RapidMiner, a maker of predictable analytics software, took 5,000 sq. ft. at 10 Fawcett Street in West Figure 1: Office Vacancy Rate vs. Lease Rate Vacancy Rate 7.1% Average Asking Lease Rate $42.62 Gross 15% $50 10% 5% 0% Q1 2010 Q2 2010 Q3 2010 Q4 2010 Q1 2011 Q2 2011 Q3 2011 Q4 2011 Vacancy (%) $30 $20 Source: CBRE Research,.

Quick Stats (Lab) Current Y-o-Y Q-o-Q Lab Vacancy 8.0% Lease Rate (NNN) $48.86 Hot Topics (Lab) 114,979 sq. ft. 750,000 sq. ft. of lab space has been delivered this quarter, including Biogen s buildings (17 Cambridge Center and 225 Binney Street) and Pfizer s building at 610 Main Street. Given active tenant requirements, a relatively modest first quarter of leasing should pick up momentum heading into the second quarter and the rest of 2014. Cambridge, while Vee24, a developer of ecommerce video chat services, took 3,000 sq. ft. at 700 Tech Square in East Cambridge. As was evident with all the small market activity, early-stage companies continue to seek value throughout the Cambridge Office market and are continuing to be forced to explore peripheral markets as rents in the East Cambridge office market hover around the $50 per sq. ft. asking rate. Lab Market The Cambridge Lab market started off 2014 with a number of small to mid-sized transactions. Overall fundamentals remained strong as the vacancy rate decreased slightly by 20 bps, rounding out at 8% for the quarter, while availability decreased by 120 bps to 18.4%. Asking rents have also decreased by $1.09 per sq. ft. in the lab market, averaging $48.86 per sq. ft. NNN for the quarter as a direct result of the quality space being absorbed by growing companies. The lab market was driven by the organic growth of local biotech companies and the expansion of major pharmaceutical companies throughout 2013, a trend that has only continued into the first quarter of 2014. The largest transactions of the quarter represented strong economic signs that Cambridge companies are continuing to experience organic growth. Aegerion Pharmaceuticals finalized an expansion and renewal at 101 Main Street for 54,000 sq. ft., of which 30,000 sq. ft. of it represented growth. Boston Biomedical also expanded their presence at 640 Memorial Drive by 43,000 sq. ft., while ModeRNA, one of the fastest growing companies in the market, took an additional 43,000 sq. ft. of expansion space at 320 Bent Street, quickly bringing their total Cambridge footprint north of 100,000 sq. ft. Three of the market s biggest construction projects were delivered this quarter, including the new Pfizer facility at 610 Main Street that will house their Cardiovascular, Metabolic and Endocrine Diseases and Neuroscience research units. Pfizer took additional space as well, signing a 12,000 sq. ft. lease at 300 Tech Square, indicating that they may already be outgrowing their new 230,000 sq. ft. building. Construction was also completed on Biogen s two new buildings, 17 Cambridge Center and 225 Binney Street, which total over 500,000 sq. ft. The new Biogen beachhead will be fully occupied with significant internal growth coupled with Biogen employees relocating from their former suburban campus in Weston. Figure 2: Market Statistics Market Rentable Area (Sq. Ft.) Availability Vacancy Sublease Quarterly Net Absorption (Sq. Ft.) Avg. Asking Rent ($/Sq. Ft./YR) Cambridge East 7,198,789 8.9% 6.0% 1.6% 43,352 $48.70 Cambridge Mid 1,870,936 6.6% 6.5% 3.9% (15,856) $35.12 Cambridge West 1,927,834 17.4% 12.0% 11.2% 16,942 $32.48 Cambridge Office 10,997,559 10.0% 7.1% 3.6% 44,438 (Gross) $42.62 Cambridge East 8,633,061 15.2% 6.9% 9.8% 116,027 $51.11 Cambridge Mid 593,817 28.0% 25.6% 1.7% (1,048) $46.41 2 Cambridge West 812,480 46.3% 6.9% 0.4% 0 $41.60 Cambridge Lab 10,039,358 18.4% 8.0% 8.6% 114,979 (NNN) $48.86 Source: CBRE Research,.

Lab Vacancy/Availability & Rent Cambridge lab availability decreased to 18.4% for the quarter, down 120 bps from last quarter, but still up year-over-year by 60%. Vacancy is up 40 bps quarter-over-quarter, but still remains at a low 8%. The East Cambridge market continues to be tight with a 6.9% vacancy rate for the quarter as large block options are limited. Average asking rents for the quarter were $48.86 per sq. ft. Office Vacancy/Availability & Rent The Cambridge Office market still remains one of the tightest markets nationally, however vacancy this quarter increased marginally by 80 bps to 7.1%. Availability remained relatively flat at 10%, with a lack of viable options for large office tenants continuing to be a trend. As a result, rents have slightly decreased to $42.62 per sq. ft., as the only space vacant is not desirable for tenants looking in the market. Figure 3: Lab Vacancy/Availability & Rent $58 23% $56 21% $54 19% $52 17% $50 15% $48 13% $46 11% $44 9% $42 7% 5% Figure 4: Office Vacancy/Availability & Rent Vacancy 8.0% Availability 18.4% Lease Rate $48.86 NNN Vacancy/Availability (%) Source: CBRE Research,. Vacancy 7.1% Availability 10.0% Lease Rate $42.62 Gross $44 20% $41 16% $38 12% $35 8% Vacancy/Availability (%) $32 4% $29 0% Figure 5: Transactions of Note Source: CBRE Research,. Tenant Address Sq. Ft. Submarket Type Office VMware 5 Cambridge Center 69,552 East Cambridge Renewal Aegerion Pharmaceuticals 101 Main Street 53,818 East Cambridge Expansion/Extension InsightSquared 160 Second Street 15,371 East Cambridge New Leaf 215 First Street 15,077 East Cambridge New BBN/Raytheon 10 Fawcett Street 12,173 West Cambridge Renewal Lab Boston Biomedical 640 Memorial Drive 42,989 East Cambridge Expansion ModeRNA 320 Bent Street 42,638 East Cambridge Expansion 3 Idera Pharmaceuticals 167 Sidney Street 26,589 East Cambridge Renewal BioAnalytix 790 Memorial Drive 3,788 East Cambridge New Source: CBRE Research,.

Figure 6: Economic Conditions Venture Capital Funding In the first quarter of 2014 Massachusetts companies raised $899 million in venture capital funding an increase of nearly 50% compared to the same period last year. While health care has consistently dominated Massachusetts share of VC funding, the Internet sector topped health care for the first time in five quarters as reported by CB Insights. Greater Boston is second only to Silicon Valley in receiving VC funds in the United States. Boston and Silicon Valley attract the most VC funding of any region in the U.S., accounting for 52% of the nation's investments. In 2013, companies in Greater Boston received $3.3 billion in VC funding. This is $92 million more than all the companies in the NY Metro area combined. Software and biotechnology continue to be the largest sectors for dollars invested in the U.S. in 2013. BILLIONS ($) $120 $100 $80 $60 $20 $0 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 United States Silicon Valley Greater Boston Source: PWC MoneyTree and CB Insights. DEFINITIONS Average Asking Lease Rate Rate determined by multiplying the asking gross lease rate for each building by its available space, summing the products, then dividing by the sum of the available space with net leases for all buildings in the summary. Net Leases Includes all lease types whereby the tenant pays an agreed rent plus estimated average monthly costs of the operating expenses and taxes for the property, including utilities, insurance and/or maintenance expenses. Market Coverage Includes all competitive buildings in CBRE s survey set. The change in occupied sq. ft. from one period to the next, as measured by available sq. ft.. Net Rentable Area The gross building square footage minus the elevator core, flues, pipe shafts, vertical ducts, balconies and stairwell areas. Occupied Area (Sq. Ft.) Building area not considered vacant. Under Construction Buildings that have begun construction as evidenced by site excavation or foundation work. Available Area (Sq. Ft.) Available building area that is either physically vacant or occupied. Availability Rate Available sq. ft. divided by the net rentable area. Vacant Area (Sq. Ft.) Existing building area that is physically vacant or immediately available. Vacancy Rate Vacant building feet divided by the net rentable area. Normalization Due to a reclassification of the market, the base, number and square footage of buildings of previous quarters have been adjusted to match the current base. Availability and vacancy figures for those buildings have been adjusted in previous quarters. 4

CAMBRIDGE SUBMARKETS CONTACT For more information about this Local MarketView, please contact: +FOLLOW US U.S. RESEARCH Suzanne Duca Director of Research New England Research CBRE, 33 Arch Street, 28th Floor Boston, MA 02110 t: +1 617 912 7041 f: +1 617 912 7001 e: suzanne.duca@cbre-ne.com WWW.CBRE-NE.COM GLOBAL RESEARCH AND CONSULTING This report was prepared by the CBRE U.S. Research Team, which forms part of CBRE Global Research and Consulting a network of preeminent researchers and consultants who collaborate to provide real estate market research, econometric forecasting and consulting solutions to real estate investors and occupiers around the globe. DISCLAIMER Information contained herein, including projections, has been obtained from sources believed to be reliable. While we do not doubt its accuracy, we have not verified it and make no guarantee, warranty or representation about it. It is your responsibility to confirm independently its accuracy and completeness. This information is presented exclusively for use by CBRE clients and professionals and all rights to the material are reserved and cannot be reproduced without prior written permission of the CBRE Global Chief Economist. 5