International Conference of translational medicine on pathogenesis and therapy of immunomediated diseases

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International Conference of translational medicine on pathogenesis and therapy of immunomediated diseases Innate immunity, inflammation and experimental models of human diseases www.translationalimmunology.it PRELIMINARY SCIENTIFIC PROGRAM CONFERENCE VENUE Aula Magna Via Festa del Perdono, 7 Milan UNDER THE AUSPICES OF SIICA SECRETARIAT Rita Repizzi Tel. +39 333 4398196 siica.amministrazione@siica.it www.siica.org Follow us on FACEBOOK ORGANIZING SECRETARIAT Viale G. Matteotti, 7 50121 Florence Italy Ph. +39 055 50351 www.oic.it siica2019@oic.it OIC Srl is a MedTech Trusted Partner

STEERING COMMITTEE Francesco Annunziato Massimo Locati Domenico Mavilio SCIENTIFIC COMMITTEE Francesco Annunziato Flavia Bazzoni Ennio Carbone Marco Cassatella Raffaele De Palma Francesca Di Rosa Armando Gabrielli Francesca Granucci Massimo Locati Enrico Lugli Domenico Mavilio Luis Montaner William Nauseef Luigi Notarangelo Isabella Quinti Angela Santoni Anna Villa

THURSDAY, 16 th MAY 2019 13.00-17.00 SATELLITE SYMPOSIUM 17.00-17.30 OPENING CEREMONY - Welcome and Opening Remarks Massimo Locati, University of Milan and Humanitas Research Hospital, Domenico Mavilio, University of Milan and Humanitas Research Hospital, Angela Santoni, La Sapienza University, Rome, Italy 17.30-19.15 SESSION 1 - FROM AUTOINFLAMMATION TO AUTOIMMUNITY Sponsored by Society of Leukocyte Biology & Journal of Leukocyte Biology Ivona Aksientevich, National Institutes of Health, Bethesda, USA William Nauseef, University of Iowa, Iowa City, USA 17.30-17.50 Manfred Boehm, National Institutes of Health, Bethesda, USA 17.50-18.00 Selected Abstract 18.00-18.20 Anna Villa, CNR and San Raffaele Institute, 18.20-18.30 Selected Abstract 18.30-18.50 Ivona Aksientevich, National Institutes of Health, Bethesda, USA 18.50-19.00 Selected Abstract 19.00-19.15 Discussion panel 19.15-20.00 OPENING KEYNOTE LECTURE Chair: Anna Villa, CNR and San Raffaele Institute, Luigi Notarangelo, National Institutes of Health, Bethesda, USA 20.20 Welcome cocktail for all Delegates

FRIDAY, 17 th MAY 2019 09.00-09.45 KEYNOTE LECTURE Chair : Luigi Notarangelo, National Institutes of Health, Bethesda, USA Jean-Laurent Casanova, Rockfeller University, New York, USA 09.45-12.15 SESSION 2 - IMMUNODEFICIENCIES Luigi Notarangelo, National Institutes of Health, Bethesda, USA Anna Villa, CNR and San Raffaele Institute, 09.45-10.10 Dan Kastner, National Institutes of Health, Bethesda, USA 10.10-10.20 Selected Abstract 10.20-10.50 Coffee break 10.50-11.15 Yanick J. Crow, INSERM, Paris, France 11.15-11.25 Selected Abstract 11.25-11.50 Steve Holland, National Institutes of Health, Bethesda, USA 11.50-12.00 Selected Abstract 12.00-12.15 Discussion panel 12.30-14.00 SATELLITE SYMPOSIUM 14.00-15.00 POSTER VIEW

FRIDAY, 17 th MAY 2019 15.00-18.15 SESSION 3 - AUTOIMMUNITY Francesco Annunziato, University of Florence, Florence, Italy Pierluigi Meroni, Istituto Gaetano Pini, 15.00-15.25 Armando Gabrielli, University of Ancona, Ancona, Italy 15.25-15.35 Selected Abstract 15.35-16.00 Chatila Talal, Harward University, Boston, USA 16.00-16.10 Selected Abstract 16.10-16.40 Coffee break 16.40-17.05 Ciriaco A. Piccirillo, Montreal Diabetes Research Center, Montreal, Quebec, Canada 17.05-17.15 Selected Abstract 17.15-17.30 Discussion panel 17.30-18.15 KEYNOTE LECTURE Chair: Angela Santoni, La Sapienza University, Rome, Italy Abul Abbas, University of California, San Francisco, USA 20.00 Social Dinner

SATURDAY, 18 th MAY 2019 09.00-09.45 KEYNOTE LECTURE Chair: Domenico Mavilio, University of Milan and Humanitas Research Hospital, Lewis Lanier, University of California, San Francisco, USA 09.45-12.15 SESSION 4 - IMMUNITY TO INFECTIONS Domenico Mavilio, University of Milan and Humanitas Research Hospital, Luis Montaner, Wistar Institute, Philadelphia, USA 09.45-10.10 Rino Rappuoli, GlaxoSmithKline Vaccines, Siena, Italy 10.10-10.20 Selected Abstract 10.20-10.50 Coffee break 10.50-11.15 Guido Silvestri, Emory University, Atlanta, USA 11.15-11.25 Selected Abstract 11.25-11.50 Paolo Lusso, National Institutes of Health, Bethesda, USA 11.50-12.00 Selected Abstract 12.00-12.15 Discussion panel 12.30-14.00 SATELLITE SYMPOSIUM 14.00-15.00 POSTER VIEW 15.00-15.45 KEYNOTE LECTURE Chair: Antonio Sica, University of Piemonte Orientale and Humanitas Research Hospital, Alberto Mantovani, Hunimed and Humanitas Research Hospital,

SATURDAY, 18 th MAY 2019 15.45-18.15 SESSION 5 - TUMOR IMMUNOLOGY Massimo Locati, University of Milan and Humanitas Research Hospital, Angela Santoni, La Sapienza University, Rome, Italy 15.45-16.10 Massimiliano Pagani, University of Milan and Istituto Nazionale Genetica Molecolare, 16.10-16.20 Selected Abstract 16.20-16.50 Coffee break 16.50-17.15 TBD 17.15-17.25 Selected Abstract 17.25-17.40 Discussion panel 17.40-19.00 TRIBUTE AND MEMORIAL TO ALESSANDRO MORETTA (1953-2018) Chair: Domenico Mavilio, University of Milan and Humanitas Research Hospital, 17.40-17.50 Angela Santoni, La Sapienza University, Rome, Italy 17.50-18.00 Franco Locatelli, Ospedale Bambin Gesù, Rome, Italy 18.00-18.45 KEYNOTE LECTURE IN MEMORY OF ALESSANDRO MORETTA Chair: Lorenzo Moretta, Ospedale Bambin Gesù, Rome, Italy Eric Vivier, University of Marseille, Marseille, France 18.45-18.50 Award Ceremony for the best Poster / Presentation on NK Cell Biology entitled to Alessandro Moretta 19.00-19.10 FAREWELL Massimo Locati, University of Milan and Humanitas Research Hospital, Domenico Mavilio, University of Milan and Humanitas Research Hospital,