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UBC BC CANCER REB MEMBERSHIP HISTORY OF CHANGES: d August 14, 2018 UBC BC Cancer Research Ethics Board (REB) institution or organization (IORG) : IORG0003172 UBC Federal Wide Assurance Number for U.S. government studies: FWA00001149 UBC BC Cancer REB IRB Registration Number: IRB00003797 UBC BC CANCER REB REB 67 2018Aug14 Added: Dr Parveen Bhatti 14 Aug 2018 New 352959 2021Aug14 66 2018Jul16 Added: Dr Yalin Yin Removed: Dr Sophie Sun, Dr Robert Olson, Mr Simon Kent, Ms Suzanne Kennedy, Ms Sarah Harbottle, Dr J Russell 65 2018Mar13 Changed: Dr Karen Gelmon (Member to Chair) Changed: Dr Vivien Bramwell (Chair to Vice-Chair) Removed: Dr Joseph Connors Changed: BC Cancer Agency to BC Cancer 64 2017Oct30 Added: Dr Karen Gelmon Added: Dr Jim Rose Added: Dr Amrit Khalon 63 2017Aug16 Removed: Dr Ken Swenerton, Chair Changed: Dr Vivien Bramwell (Vice-Chair to Chair) 1 Jul 2018 1 Mar 2018 30 Oct 2017 16 Aug 2017 352675 2021Jul16 311655 2021Mar13 210425 2020Oct 30 199714 2020Aug16 266709, OMB 0990-0278 Expiry: 2023Mar07 62 2017May15 Added: Dr Joseph Connors (alternate for K Swenerton/V Bramwell) 15 May 2017 148892 2020May15 61 2017Mar31 Changed: REB mailing/location address from: 902-750 W Broadway to 1315-W Broadway, Vancouver, BC. 31 Mar 2017 138539 2020Mar31 Page 1 of 6

New 60 2017Mar14 Added: Dr Sharlene Gill Added: Dr Anna Tinker Added: Ms Katherine Sunderland Changed: Dr Nhu Le (alternate to primary statistician) Changed: Dr John Spinelli (primary to alternate statistician) Removed: Dr Yaling Yin (alternate statistician) 59 2017Feb17 Added: Mr Michael Kleisinger (alternate for S Harbottle) Added: Dr Aline Talhouk (alternate for J Spinelli) Changed: Ms S Kennedy (from primary to alternate) Removed: Dr Douglas Ozier 58 2016Oct18 Added: Dr Aalok Kumar Added: Dr Nina Preto (alternate for H Longstaff) Changed: Ms S Kennedy to primary Changed: Mr S Kent to alternate for S Kennedy 57 2016May03 Removed: Dr David Fenton Removed: Ms Loree Phillet 56 2016Mar16 Added: Ms Sylvie Labelle-Stimac Added: Dr. Marilyn Borugian Removed: Dr. Terry Boyle Changed: Head Official for the BC Cancer Agency from Nick Foster to Malcom Moore 55 2016Mar15 2015Aug10 54 2015Aug09 2015Feb18 53 2015Feb18 2014Sep15 52 2014Sep14 2014May01 Added: Dr. Robert Olson Added: Dr. Doran Ksienski Removed: Dr. Howard Lim Removed: Dr. David Voduc Changed: a) Head Official for the BC Cancer Agency from Max Coppes to Nick Foster b) Removed BREB B as designated IRB on FWA as now merged with BREB A Added: Dr. Douglas Ozier Added: Dr. Isabelle Vallieres Removed: Dr. Lorna Weir Removed: Ms. Brenda Bird-Cantelon Added: Dr. Terry Boyle Removed: Dr. Johnna Fisher Removed: Dr. George Browman Removed: Joanne Stephen 14 Mar 2017 17 Feb 2017 1 Oct 2016 2016Apr27 2016Feb01 2016Mar01 2016Jan31 138389 117468 117057 85357 64906 2015Aug01 2015Aug01 2015Jun30 2015Jul21 42411 2015Feb01 2015Feb01 2015Jan31 2015Feb01 2014Sep15 2014Jun01 2014Apr30 2014Apr30 2020Mar14 2020Feb17 2019Oct18 2019May03 2019Mar16 2018Aug10 40898, OMB 0990-0278 Expiry: 2021Mar09 40473 2018Feb18 38136 2017Jul03 37511 2017May02 38461, OMB 0990-0278 Expiry: 2020Feb18 UBC BC Cancer REB Membership History of Changes: August 14, 2018 Page 2 of 6

New 51 2014Apr30 2014Mar31 50 2014Mar30 2014Feb01 49 2014Jan31 2014Jan28 48 2014Jan27 2014Jan01 47 2013Dec31 2013Nov01 46 2013Oct31 2013Oct01 45 2013Sep31 2013Mar01 44 2013Feb28 2013Feb01 43 2013Jan31 2013Jan01 42 2012Dec31 2012Nov22 41 2012Nov21 2012Oct23 40 2012Oct22 2012July01 39 2012Jun30 2012May01 Changed: REB Chair from Dr. George Browman to Dr. Ken Swenerton 36161, Expiry 2019Apr10 Added: Dr. Ken Swenerton 2014Mar31 37325 2017Apr21 Added: Dr. Vivien Bramwell 2014Mar31 37157 2017Mar27 Added: Dr. Holly Longstaff 2014Feb01 Added: Dr. Heather Sutherland 2014Feb01 38136 2017Feb18 Added: Dr. Johnna Fisher 2014Jan28 Removed: Ms. Nina Preto Correction: Postal code for REB Office Removed: Dr. Paul Galbraith Removed: Dr. Yasser Abou Mourad Changed: Ms. Nina Pretp from alternate ethicist to primary ethicist Changed: Ms. Alice Hawkins Virani from primary ethicist to alternate ethicist Added: Ms. Nina Preto Added: Dr. Yaling Yin Added: Dr. Joanne Stephen Added: Dr. Winkle Kwan Changed: Change Brian Schmidt, BCCA Interim President to Max Coppes, BCCA President as Head Official for the BC Cancer Agency. Removed: Dr. Lee Ann Martin Removed: Dr. Maria Vlachaki d: Alice Hawkins as follows: name to Alice Hawkins Virani; Degree now PhD; Status now Canadian Permanent Resident Added: Ms. Sarah Harbottle 2013Dec31 36370 2017Jan09 2013Oct31 2013Oct31 2013Oct01 2013Mar01 2013Mar01 2013Feb01 2013Feb01 35797 2016Oct31 33304 2016Mar04 32948 2016Feb01 31840, Expiry 2018Jan29 2012Dec31 2012Nov22 2012Nov24 2012Oct23 32259 2016Jan15 Changed: Dr. Lee Ann Martin no longer REB Vice-Chair 2012July01 30691 2015Jun05 Added: Ms. Kimberly Kuik Added: Ms. Alice Hawkins Removed: Dr. Abdul Al-Tourah Removed: Dr. Lynne Nakashima Changed: David Levy, BCCA President to Brian Schmidt, BCCA Interim President as Head Official for the BC Cancer Agency. 2012May01 2012May01 2012Apr30 2012Apr30 30067 2015May01 29032, Expiry 2017Mar21 UBC BC Cancer REB Membership History of Changes: August 14, 2018 Page 3 of 6

New 38 2012Apr30 2012Mar15 37 2012Mar14 2012Mar01 36 2012Feb29 2012Feb15 35 2012Feb14 34 2012Jan31 2012Jan01 33 2011Dec31 2011Jun01 32 2011May31 2011Mar01 31 2011Feb28 2010Mar01 30 2010Feb28 2010Feb01 29 2010Jan31 2010Jan01 28 2009Dec31 2009Sep01 27 2009Aug31 2009Jul01 26 2009Jun30 2009Jun01 25 2009May31 2009Feb01 Added: Dr. Ardis Krueger 2012Mar15 Added: Dr. John Russel 2012Mar15 Added: Dr. Delia Sauciuc 2012Mar01 29650 2015Mar19 Removed: Dr. Robin O Brien 2012Feb29 Added: Dr. Daniel Renouf Added: Dr. Maria Vlachaki Added: Dr. Lorna Weir Removed: Dr. Peter Battershill 2012Jan31 Removed: Dr. Islam Mohamed 2012Jan31 28837 2015Feb15 Removed: Dr. Caroline Halloway 2011Dec31 Removed: Dr. Sanjay Rao 2011Dec31 Removed: Dr. Susan Ellard 2011Dec31 Added: Mr. Jeremy Hamm 2011Jun01 26832 2014Jun06 Removed: Dr. Maxine Alford (Mueller) 2011Feb28 25934 2014Mar01 Removed: Ms. Joan Rush 2010Feb28 22968 2013Mar12 Removed: Dr. Caroline Lohrisch 2010Jan31 22831 2013Mar02 Changed: Brian Schmidt, BCCA Interim President to David Levy, President as Head Official for the BC Cancer Agency. Added: Dr. Sophie Sun Added: Dr. Paul Galbraith Added: Dr. Islam Mohamed d: Dr. Lee Ann Martin now Vice-Chair Removed: Dr. Joseph Connors Removed: Dr. Mira Keyes Changed: Dr. Sutcliffe, BCCA President to Brian Schmidt, BCCA Interim President as the Head Official for the BC Cancer Agency. Removed: Dr. Jonn Wu Added: Dr. Hannah Carolan Added: Dr. David Voduc Removed: Dr. Hagen Kennecke Added: Dr. Howard Lim d: Dr. Abdul Al-Tourah; status now Canadian Permanent Resident 22312, Expiry 2013Jan27 2010Jan01 2010Jan01 2009Sep01 2009Sep01 2009Jun30 2009Jun30 22325 2012Jun30 20892 2012Sep04 *done on an FWA update rather than an IRB update 19989, Expiry 2012Jul07 19989, Expiry 2012Jul07 2009May31 2009Jun01 2009Jun01 2009Jan31 2009Feb01 2009Feb01 19684 2012Jun02 18817 2012Feb23 UBC BC Cancer REB Membership History of Changes: August 14, 2018 Page 4 of 6

New 24 2009Jan31 2008Oct21 23 2008Oct20 2008Sep20 22 2008Sep19 2008Aug15 21 2008Aug14 2008Jul21 20 2008Jul20 19 2008Feb29 2008Jan01 18 2007Dec31 2007Nov27 17 2007Nov26 2007Nov01 16 2007Oct31 2007Sep18 15 2007Sep17 2007Sep01 14 2007Aug29 2007Jun01 13 2007May31 2007Apr15 d: Dr. Peter Battershill now BCCA affiliated 2008Oct21 18089 2011Oct23 Removed: Dr. Antoinette Semenya 2008Sep20 17877 2011Set23 Added: Dr. Lee Ann Martin d: Loree Phillet now alternate for Jo-Ann Isaacson Added: Dr. Antoinette Semenya Removed: Mr. Chris Bardon d: Dr. Caroline Halloway moving to BCCA VIC. Dr. Ellard no longer an alternate for Dr. Halloway Added: Ms. Brenda Bird-Cantelon Added: Ms. Suzanne Kennedy Added: Mr. Ryan Woods Removed: Ms. Kathering Arnold d: Dr. Kennecke attending 50% of meetings; Dr. Lohrisch will attend each meeting. Correction: Dr. Al-Tourah: Permanent Resident Status is pending Added: Dr. Abdul Al-Tourah Added: Dr. Caroline Halloway Added: Mr. Simon Kent Removed: Dr. Kevin Song Added: Dr. Yasser Abou Mourad 2008Aug15 17630 2011Aug18 2008Jul21 17595 2011Aug11 2008Feb29 16705 2011Mar17 2008Jan01 16210 2011Jan03 2007Nov27 2007Nov01 16154 2011Jan02 Removed: Dr. Chris Badjik 2007Sep18 16057 2010Nov29 Removed: Dr. Paul Blood d: Dr. Lorhrisch and Dr. Kennecke alternating d: Mr. Chris Bardon affiliation to BCCA d to YES (spouse of Dr. Lohrisch) 2007Aug29 2007Sep01 15592 2010Nov06 Removed: Dr. Maria Cristina Barroetavena 2007Jun01 15346 2010Aug14 d: Dr. Peter Battershill d to non-affiliated 2007Apr15 14943 2010May24 UBC BC Cancer REB Membership History of Changes: August 14, 2018 Page 5 of 6

New 12 2007Apr14 2006Mar01 11 2007Feb28 2006Aug01 10 31Jul2006 2006Apr01 9 2006Mar31 2006Feb06 8 2006Feb05 2005Dec01 7 2005Nov30 2005Sep15 6 2005Sep14 2005Jul01 5 2005Jun30 2004Jun08 4 2004Jun07 2004Jun01 3 2004May31 2004May01 2 2004Apr30 2003Oct15 1 2003Oct14 2003May27 Added: Dr. George Browman (New REB Chair) d: Dr. Joseph Conners (REB Vice-Chair) d: Dr. Lynne Nakashime (REB Second Vice-Chair) Removed: Dr. Frances Wong Removed: Dr. Ken Swenerton Removed: Dr. Paul Hoskins Added: Dr. Jonn Wu 2007Mar01 14502 2010Mar01 Added: Dr. Robin O Brien 2006Aug01 13516 2009Sep13 Added: Dr. Mira Keyes Added: Ms. Loree Phillet d: Dr. Frances Wong to alternate with Dr. Keyes Added: Dr. Peter Battershill Removed: Dr. Lori d'agincourt-canning Added: Dr. Sanjay Rao d: Dr. Ellard alternate for Dr. Rao Added: Dr. Kevin Song Added: Dr. Caroline Lohrisch d: Name Change - Dr. Maxine Mueller to Dr. Maxine Alford (married 2005Jul09) Added: Dr. Chris Bajdik Removed: Dr. David Fenton 2006Apr01 12671 2009Apr10 2006Feb06 12671 2009Apr10 2005Dec01 12217 2009Feb03 2005Sep15 2005Sep15 11523 11523 11524 2008Oct26 2008Oct26 2008Nov01 2005Jul01 10906 2008Jul15 Added: Dr. Hagen Kennecke 2004Jun08 * 2007Dec06 Added: Ms. Joan Rush 2004Jun01 * 2007Dec06 Added: Ms. Katherine Arnold 2004May01 * 2007Dec06 Format only (no other ) d: Addendum added (only OHRP expiry date d) Added: First REB Membership created 2003May27 2230 2007Dec06 2006Sep25 *: Form was faxed and no was received. UBC BC Cancer REB Membership History of Changes: August 14, 2018 Page 6 of 6