CURRICULUM VITAE Diana Catalina, Ph.D. 214.295.0406 dcanseco@dcccd.edu EDUCATION Bachelor of Science (December 1999) Master of Science (Chemistry) (May 2003) Doctor of Philosophy-(Molecular Biology) (May 2009) Denton, Texas Denton, Texas Texas Woman's University Denton, Texas PROFESSIONAL EXPERIENCE PostDoctoral Research Fellow II Graduate Research Assistant Teaching Assistant Undergraduate Research Assistant Spanish Instructor SKILLS AND TECHNIQUES UT Southwestern Medical Center June 2009 - Present January 2000-May 2009 January 2000-May 2002 August 1998-December 1999 University of North Texas Continuing Learning Education September 1999- April 2001 1 H and 13 C NMR, FTIR, GC/MS, UV/VIS, HPLC, TLC, and Flash Chromatography. Dry box techniques. Rodent microsurgery, ovariectomy, behavior scoring including observation, small animal injection and handling. Radioligand binding assay including saturation isotherm assays and inhibition assays. PCR,DNA sequencing, western blot, gel electrophoresis, MI, and ChIP. 1
PUBLICATIONS 1., D.C.*, Cummings, D.F.*, Sheth., P, Johnson, J.E., and Schetz, J. A., Synthesis and structure affinity relationships of novel small molecule natural product derivatives capable of discriminating between serotonin 5- HT1A, 5-HT2A, 5-HT2C receptor subtypes. Bioorg Med. Chem. 2010, 18, 4783-4792. (*These authors contributed equally to this work). 2. J. E. Johnson, D. C., D. D. Dolliver, J. A. Schetz, and F. R. Fronczek, Synthesis and Characterization of Aplysinopsin Analogs, J. Chem. Crystallography, 2009, 39, 329-336. 3. J. E. Johnson, C. Carvallo, D. D. Dolliver, N. Sanchez, V. Garza, D. C., G. L. Eggleton, and F. R. Fronczeck. Bisamidoximes: Synthesis and Complexation with Iron (III), Aust. J Chem. 2007, 60, 685-690. 4. D. D. Dolliver, S. Smith, D. B. Delatte, K. D. Patel, T. E. Thomas, J. Chagnard J.E. Johnson, D.C., F. R. Fronczek, C. D. Bryan, J. E. Rowe, and A. S. McKim, Synthesis of N-AlkoxyimidoyI iodides and a Comparison of Their Structure to Other N-Alkoxyimines, J. Chem.Crystallography, 2007, 37, 837-846. 5. D. D. Dolliver, D. B. Delatte, D. B. Linder, J. E. Johnson, D. C., and J. E. Rowe, Nucleophilic Substitution Reactions of N-Alkoxyimidoyl Fluorides by Carbon Nucleophiles, Can. J. Chem., 2007, 85, 913-922. 6. J. E. Johnson, D. C., D. D. Dolliver, J. E. Rowe, and F. R. Fronzcek, Synthesis, Characterization, and Structural Analysis of Ethyl (2Z)-3-(4- Chlorophenyl)-2-cyano-3-(methoxyamino)prop-2-enoate, J. Chem.Crystallography, 2006, 36, 667-672. 7. J. E. Johnson, L. Lu, H. Dai, D. C.. D. Dolliver, and F. R. Froncezek, "Synthesis and Characterization of, Unsaturated Hydroximoyl Chlorides and Hydroximates," Aust. J. Chem. 2006, 59, 439-444. 8. J. E. Johnson, D. C., and J. E. Rowe, The Preparation of Methyl (E)- and (Z)-O-Methylbenzothiohydroximates, Aust. J. Chem. 2004, 57, 549-552. 9. J. E. Johnson, D. D. Dolliver, L. Yu, D. C., M. A. McAllister, and J. E. Rowe, "Mechanism of Methoxide Ion Substitution on the Z and E Isomers of O-Methylbenzohydroximoyl Halides," J. Org. Chem., 2004, 69, 2741-2749. 2
10. J. Ni, Q. Zhou, D. C., T. Callhoun, A. Graham, K. Carreras, C. Schultz, Transformations of carbon dioxide to methoxide by the complex [(C 5 H 5 )Ti] 2 ( -H) 2 ( -C 10 H 8 ), Inorganica Chimica Acta. 2000, 309, 23-27. PAPERS PRESENTED AT MEETINGS SINCE 1999 1. D., J. E. Johnson, and J. A. Schetz, Synthesis and Screening of Aplysinopsin Analogs as Possible Serotonin Receptor Ligands National Institute of Health, Graduate Research Festival, Bethesda, MD., October 2007. 2, D., J. E. Johnson, and H. Dai, "Acid-Catalyzed Z/E Isomerization of Methyl O-Methylbenzothiohydroximates," Texas Woman's University Research Symposium, April 2005. 3. D. and J. E. Johnson, "Acid-Catalyzed Z/E Isomerization of Methyl O-Methylbenzothiohydroximates," Texas Woman's University Research Symposium, April 2004. 4. D. and J. E. Johnson, "Acid-Catalyzed Z/E Isomerization of Methyl O-Methylbenzothiohydroximates," Annaul Biomedical Research Conference for Minority Students, November 2004. 5. J. E. Johnson, H. Dai and D., "Mechanism of Acid-Catalyzed Z/E I somerization of Imines in Acetonitrile," National Meeting of the American Chemical Society, New Orleans, LA, March 26, 2003, Abstract No. ORGN 483. 6. D., and H. Dai, "Mechanism of Acid-Catalyzed Z/E Isomerization of Imines in Acetonitrile," Texas Woman's University Symposium, April 2003. 7. D., J. E. Johnson, D.Dolliver and J. E. Rowe, "Synthesis and Mechanism of Acid-Catalyzed Z/E Isomerization of Methyl O- Methylbenzothiohydroximates," Annual Biomedical Research Conference for Minority Students, November, 2002. 8. I Atamah, J. E. Johnson, A. Jackson, D., D. Dolliver, J. E. Rowe, and S. Bott., "Nucleophilic Substitution of O-Alkylbenzohydroximoyl Fluorides by Grignard Reagents and Enolate Anions. A new Method for the Synthesis of O-Alkyloximes," Annaul Biomedical Research Conference for Minority Students, November, 2002. 9. D. K., Houquan Dai, and J. E. Johnson, "Mechanism of Acid- Catalyzed Z/E Isomerization of N-Methoxyimines" MORE Symposium, 2001. 3
10. D., Cuong Nguyen and J. E. Johnson, "Synthesis, Identification, and Mechanism of Acid-Catalyzed Z/E Isomerization of Methyl O- Methylthiohydroximates, TWU Student Research Symposium, 2001. 11. J. E. Johnson, D. K., E. J. Clabiorne, D.D. Dolliver, M. A. McAllister, and J. E. Rowe Synthesis, Identification, and Mechanism of Acid-Catalyzed Z/E Isomerization of Methyl O-Methylthiohydroximates, 221 st National Meeting of the American Chemical Society, San Diego, CA, April 3, 2001, Abstract No.ORGN 352. 12. D. K., E. Clabiorne, and J. E. Johnson, "Synthesis and Identification of the Z and E Isomers of Methyl O- Methylbenzothiohydroximates," 2000 NIGMS Minority Research Symposium," Washington D.C., November 10, 2000, Abstract G68. 13. J. Ni, Q. Zhou, D. K., T. Callhoun, A. Graham, K. Carreras, C. Schultz, Transformations of carbon dioxide to methoxide by the complex [(C 5 H 5 )Ti] 2 ( -H) 2 ( -C 10 H 8 ), 1999 NIGMS Minority Research Symposium," Phoenix, AZ, November 10, 1999, Abstract A68. ORAL PRESENTATIONS D., Synthesis and Screening of Aplysinopsin Analogs as Possible Serotonin Receptor Ligands The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), January 9 th, 2008. D., Synthesis of novel substrates as possible serotonin receptor ligands, Research Appreciation Day, University of North Texas Health Science Center, April 6 th, 2007. D., "Synthesis and Mechanisms of Acid-Catalyzed Z/E Isomerization of Methyl O-methylbenzothiohydroximates", American Chemical Society-Dallas-Fort Worth Section, 39th Annual Meeting in Minature, Texas Woman's University, April 29, 2006. D., "Synthesis of Novel Substrates for 5HT2 receptors", Student Creative Arts and Research Symposium, Texas Woman's University, April 18, 2006. D., "Attempts to synthesize novel substrates for 5HT2 receptors," Multi-Ethic Biomedical Research Support Program, Texas Woman's University, October 14, 2005. D., "Acid-Catalyzed Isomerization of Hydroximates and Thiohydroximates," Multi-Ethic Biomedical Research Support Program, Texas Woman's University, October 15, 2004. 4
AWARDS/HONORS April 2008 August 2007 April 2007 April 2006 April 2005 Chancellor s Student Research Scholar Award NIH National Graduate Student Research Festival Chancellor s Student Research Scholar Award Chancellor's Student Research Scholar Award Chancellor's Student Research Scholar Award 2000 2009 Member of Multi Ethnic Biomedical Research Support Program 2000 2003 Willis-Clark Scholarship 2002-2009 Graduate Student Scholarship UNIVERSITY SERVICE 1. Student representative for the Multi Ethnic Biomedical Research Support Program, 2000-2001, 2002-2003 and 2004-Present 2. Member of the Annual Research Symposium Committee at Texas Woman s University, 1999-2000 3. President of the Chemistry Club at, 1998-1999 PROFESSIONAL MEMBERSHIPS Sigma Xi Society American Chemical Society Society for Neuroscience Tri-Beta Biological Honor Society 5
COMMUNITY SERVICE Volunteer work at Children s Medical Center (Dallas), Fall 2000-Spring 2002 INTERESTS IN EXTRACURRICULAR AREAS Photography, music, swimming, running, and golf 6