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September 15th 16th, 2017 Berlin, Germany Course Directors Gerald S. Werner, Darmstadt, Germany Alexander Bufe, Krefeld, Germany Markus Meyer-Gessner, Duesseldorf, Germany Ulf Landmesser, Berlin, Germany ECC-President Alfredo R. Galassi, Catania, Italy Co-Directors Nicolas Boudou, Toulouse, France Luca Grancini, Milan, Italy Alexander Lauten, Berlin, Germany FINAL PROGRAM www.eurocto2017.com

INDEX Scientific Program: Friday, September 15th, 2017 07 Scientific Program: Saturday, September 16th, 2017 10 Faculty 15 Euro CTO Club 16 Sponsors 26 General Information 27 3

COURSE DIRECTORS ECC-PRESIDENT CO-DIRECTORS Gerald S. Werner, Darmstadt, Germany Alexander Bufe, Krefeld, Germany Markus Meyer-Gessner, Duesseldorf, Germany Ulf Landmesser, Berlin, Germany Alfredo R. Galassi, Catania, Italy Nicolas Boudou, Toulouse, France Luca Grancini, Milan, Italy Alexander Lauten, Berlin, Germany Dear Colleagues, Dear Friends, Interventional therapy of chronic total occlusions has achieved a success rate almost in the range of non-cto lesions. The previous meetings were a great success, as the feedback from the attending physicians clearly shows that such focused meetings are of great value covering the topic in a fashion that is not possible in major Interventional meetings with broader interests. It is a great opportunity to gather together and to discuss major issues, such as the continuous education, techniques and product development, research in the field, and many others. Gerald S. Werner, Alexander Bufe, Markus Meyer-Gessner, Ulf Landmesser Course Directors Nicolas Boudou, Luca Grancini, Alexander Lauten Course Co-Directors Alfredo R. Galassi Euro CTO Club President What are the reasons behind this success? The number of studies performed in the field of CTOs has increased considerably, and we shall provide an up-to-date overview of current knowledge. The major randomized study to consolidate the indication for CTO PCI will be available at that time, the EURO-CTO trial, and we have ample time to discuss the impact the future increase of CTO PCI. For the third time Live cases will be part of the program. With Berlin in the center of Europe, we offer you both an attractive place and a geographically ideal site. We look forward to meeting all of you in Berlin. 4 5

SCIENTIFIC PROGRAM Friday, September 15th, 2017 07:00 Registration 08:00 10:15 08:00 08:10 08:20 08:35 08:50 Session 1: CTO PCI STEP BY STEP I Chairmen: Nicolaus Reifart, Germany; Alfredo R. Galassi, Italy What do we need to indicate CTO PCI? Anthony Gershlick, United Kingdom Angiogram how to record, analyse and prepare for the intervention Andrea Gagnor, Italy Antegrade step by step approach Markus Meyer-Gessner, Germany Retrograde step by step approach Evald Høj Christiansen, Denmark LIVE CASES Discussants: Mark Rosenberg, Germany; Victoria Martin Yuste, Spain; Artis Kalnins, Latvia; Guy Heyndrickx, Belgium Live Case 1 Osamu Katoh, Japan; Kambis Mashayekhi, Germany Live Case 2 Heinz Joachim Büttner, Germany; Nicolas Boudou, France 10:15 Coffee break and exhibition 10:30 12:30 10:30 10:45 10:55 11:05 11:15 11:35 Session 2: The Euro CTO Club Chairmen: George Sianos, Greece; Markus Meyer-Gessner, Germany Welcome by the Organisers Gerald S. Werner, Germany; Ulf Landmesser, Germany; Alfredo R. Galassi, Italy Euro CTO Club The Euro CTO trial Gerald S. Werner, Germany The Euro CTO Score Comparison with existing scores David Hildick-Smith, United Kingdom Euro CTO Club The radiation survey Nicolaus Reifart, Germany Recent CTO publications Carlo Di Mario, Italy LIVE CASES Discussants: Nicolas Boudou, France; Jürgen Arenz, Germany; Aigars Lismanis, Latvia; Michael Pieper, Switzerland Live Case 3 Etsuo Tsuchikane, Japan; Alexander Bufe, Germany 䌀漀洀洀椀琀琀攀搀琀漀椀洀瀀爀漀瘀攀琀栀攀漀甀琀挀漀洀攀漀昀挀漀洀瀀氀攀砀氀攀猀椀漀渀猀 7

12:30 Lunch and exhibition 17:35 End of Scientific Program 13:30 15:20 13:30 Session 3: Advances in CTO PCI Chairmen: Carlo Di Mario, Italy; Dimitri Karmpaliotis, USA New wires, what we have, what is essential, what is on the horizon George Sianos, Greece 19:30 Congress Dinner (Meeting Point 19:00 Hilton Lobby) Location: Humboldt Carré: www.humboldtcarre.de/en Only a limited number of seats available. We kindly ask you for an early booking. 13:40 13:50 14:00 14:20 15:10 Dedicated CTO kit: microcatheters, balloons, adjunctive devices Kambis Mashayekhi, Germany New developments in antegrade dissection/re-entry approach Stéphane Rinfret, Canada CASE LIVE IN A BOX Live in a Box 1 Nicolaus Reifart, Germany LIVE CASES Discussants: Thomas Schmitz, Germany; Didier Tchetche, France; Hans Bonnier, Belgium; Jaroslaw Wójcik, Poland Live Case 4 Gerald S. Werner, Germany; Luca Grancini, Italy Future Devices: Update on the Plasma wire Etsuo Tsuchikane, Japan LIVE CASES supported by unrestricted educational grants by: 15:20 Coffee break and exhibition 15:35 1735 15:35 16:25 16:35 16:45 Session 4: Specific Clinical problems and CTOs Chairmen: Alexander Bufe, Germany; Etsuo Tsuchikane, Japan LIVE CASES Discussants: Joerg Dalibor, Germany; Yves Louvard, France; Hweung Kon Hwang, Korea; Alexander Ghanem, Germany Live Case 5 George Sianos, Greece ; Tim Schäufele, Germany CTO-PCI and the need of oral anticoagulation Alexander Bufe, Germany ACS and CTO how to manage Bernward Lauer, Germany CTO and low ejection fraction Alfredo R. Galassi, Italy CASE LIVE IN A BOX 16:55 Live in a Box 2 Leszek Bryniarski, Poland Live in a Box 3 17:15 8 Omer Goktekin, Turkey 9

SCIENTIFIC PROGRAM Saturday, September 16th, 2017 06:45 Registration desk open 08:30 LIVE CASES Discussants: Sergey Furkalo, Ukraine; Alexandre Avran, France; Leszek Bryniarski, Poland; Khalid Tammam, Saudi Arabia Live Case 6 Masahiko Ochiai, Japan; Markus Meyer-Gessner, Germany Room: Ballroom Room: Salon Schinkel Live Case 7 Alfredo R. Galassi, Italy; Harald Lapp, Germany Breakfast Meeting CTO a global perspective Breakfast Meeting CTOs for (young) beginners 10:00 CTO and bifurcation Yves Louvard, France Chairmen: Alfredo R. Galassi, Italy; Etsuo Tsuchikane, Japan Chairmen: David M. Leistner, Germany; Alexander Ghanem, Germany Rapid fire Tipps and Tricks 5 min: What do do if CTO in Europe Antegrade approach how to start? 10:15 you cannot cross the proximal cap Valeri Gelev, Bulgaria Alfredo R. Galassi, Italy Views of a minimalist and a maximalist point of view combattants David M. Leistner, Germany vs. Alexander Ghanem, Germany 10:23 10:31 antegrade balloon cannot pass Imre Ungi, Hungary microcatheter cannot pass collateral Jo Dens, Belgium 07:15 CTO in the Middle East Khalid Tammam, Saudi Arabia A minimalist view David M. Leistner, Germany 10:39 Reverse CART does not work Yasushi Asakura, Japan 08:30 CTO in Japan / Asia Pacific Etsuo Tsuchikane, Japan A maximalist view Alexander Ghanem, Germany 10:47... retrograde microcather cannot pass the lesion Yasushi Asakura, Japan 10:55 Coffee break and exhibition CTO in India Surya Prakasa Rao Vithala, India Which lesion to start with which material? Thomas Schmitz, Germany 11:15 13:15 Session 6: Approach to CTO and imaging Chairmen: Heinz Joachim Büttner, Germany; Emmanouil Brilakis, USA CTO in North America Emmanouil Brilakis, USA Which setting? Top 10 lessons learned from my time as CTO beginner Gerald S. Werner, Germany 11:15 LIVE CASES Discussants: Jaroslaw Wójcik, Poland; Thierry Lefevre, France; Andrea Gagnor, Italy; Imre Ungi, Hungary Live Case 8 Dimitri Karmpaliotis, USA; Alexander Lauten, Germany What we can achieve together George Sianos, Greece When am I prepared enough for my first retrograde approach? 12:00 5 most important things you can do wrong in the antegrade approach Nicolas Boudou, France 08:30 10:55 Session 5: Specific CTO situations Chairmen: Kenya Nasu, Japan; Gerald S. Werner, Germany Kambis Mashayekhi, Germany 12:10 12:20 5 most important things you can do wrong in the retrograde approach Roberto Garbo, Italy Intracoronary Imaging when to use, how to use and how to interpret the images Javier Escaned, Spain 10 11

OPTIMISE YOUR APPROACH TO CTO LESIONS ACCESS 12:35 12:45 Long-term outcome with DES in CTOs Holger Nef, Germany BVS An option for CTOs? Michael Haude, Germany 1Fr size reduction in outer diameter compared to conventional sheaths, while keeping the large inner diameter equivalent 1,2 12:55 CASE LIVE IN A BOX Live in a Box 4 Kambis Mashayekhi, Germany PTCA Guiding Catheter Excellent shape retention for your long CTO procedure. 13:15 Lunch and exhibition 14:00 17:15 Session 7: Complex situations, Complications and Future Chairmen: Ulf Landmesser, Germany; Alfredo R. Galassi, Italy PTCA Guide wire Duo core technology for flexible steering control. 2 and Single and dual lumen microcatheters to support your guidewire in antegrade or retrograde approach CTO procedures. 3 14:00 14:50 15:05 LIVE CASES Discussants: Yves Louvard, France; Javier Escaned, Spain; Roberto Garbo, Italy; Harald Lapp, Germany Live Case 9 Alexandre Avran, France; Bernward Lauer, Germany A brief review of complications and tips and tricks Emmanouil Brilakis, USA CTO in post CABG patients Heinz Joachim Büttner, Germany IS703GB0717ITI(0717)E 1. www.terumo-europe.com (accessed March 2016). 2. Terumo. Expanding transradial access for more patients. TIS-579-05202015/TJP. 3. Terumo. Optimize your approach to complex lesions. TIS-567-06022015/TJP. 4. Muramatsu et al., Current technical and clinical features of the antegrade and retrograde approaches to percutaneous transluminal coronary intervention for chronic total occlusion, The Egyptian Heart Journal, 2014; 66:1-10 5. Kimura et al., Successful retrieval of an entrapped Rotablator burr using 5 Fr guiding catheter, Catheter Cardiovasc Interv. 2011 Oct 1;78(4):558-64 Not all products are available for sale in all countries. Please contact your Terumo local sales representative for more information. 12 13 www.terumo-europe.com PTCA Balloon Cross and recross thanks to the ultra low profile (0.40 mm). 4,5 Drug Eluting Stent Ultimaster DES has been developed combining key features to optimize its use in complex anatomy. CLOSURE 15:15 Coffee break and exhibition 15:30 15:50 16:00 16:10 CASE LIVE IN A BOX Live in a Box 5 Thierry Lefevre, France What future trials do we need in CTOs? Ulf Landmesser, Germany MSCT and navigation for CTO PCI Gerald S. Werner, Germany LIVE CASES: Summary / Discussion Summary of Live Cases 1-9 and Critical Discussion Panel with Live Operators

16:40 Closing remarks Alexander Bufe, Germany; Markus Meyer-Gessner, Germany 17:15 ECC General Assembly with Board Elections FACULTY THE EURO CTO CLUB CORDIALLY THANKS THE INVITED SPEAKERS FOR SUPPORTING THE WORKSHOP WITH THEIR KNOWLEDGE AND EXPERTISE: LIVE CASES supported by unrestricted educational grants by: GUESTS FACULTY Yasushi Asakura, Japan Emmanouil Brilakis, USA Michael Haude, Germany Hweung Kon Hwang, Korea Dimitri Karmpaliotis, USA Osamu Katoh, Japan Kenya Nasu, Japan Holger Nef, Germany Masahiko Ochiai, Japan Stéphane Rinfret, Canada Khalid Tammam, Saudi Arabia Etsuo Tsuchikane, Japan Surya Prakasa Rao Vithala, India LIVE OPERATORS Osamu Katoh, Japan / Kambis Mashayekhi, Germany Heinz Joachim Büttner, Germany / Nicolas Boudou, France Etsuo Tsuchikane, Japan / Alexander Bufe, Germany Gerald S. Werner, Germany / Luca Grancini, Italy George Sianos, Greece / Tim Schäufele, Germany Masahiko Ochiai, Japan / Markus Meyer-Gessner, Germany Alfredo R. Galassi, Italy / Harald Lapp, Germany Dimitri Karmpaliotis, US / Alexander Lauten, Germany Alexandre Avran, France / Bernward Lauer, Germany SPEAKERS, CHAIRMEN AND DISCUSSANTS Jürgen Arenz, Germany Artis Kalnins, Latvia Alexandre Avran, France Ulf Landmesser, Germany Hans Bonnier, Belgium Harald Lapp, Germany Nicolas Boudou, France Bernward Lauer, Germany Leszek Bryniarski, Poland Alexander Lauten, Germany Heinz Joachim Büttner, Germany Thierry Lefevre, France Alexander Bufe, Germany David M. Leistner, Germany Evald Høj Christiansen, Denmark Aigars Lismanis, Latvia Jörg Dalibor, Germany Yves Louvard, France Jo Dens, Belgium Victoria Martin Yuste, Spain Carlo Di Mario, Italy Kambis Mashayekhi, Germany Javier Escaned, Spain Markus Meyer-Gessner, Germany Sergey Furkalo, Ukraine Michael Pieper, Switzerland Andrea Gagnor, Italy Nicolaus Reifart, Germany Alfredo R. Galassi, Italy Mark Rosenberg, Germany Alexander Ghanem, Germany Tim Schäufele, Germany Roberto Garbo, Italy Thomas Schmitz, Germany Valeri Gelev, Bulgaria George Sianos, Greece Anthony Gershlick, United Kingdom James C. Spratt, United Kingdom Omer Goktekin, Turkey Didier Tchetche, France Luca Grancini, Italy Imre Ungi, Hungary Guy Heyndrickx, Belgium Gerald S. Werner, Germany 14 David Hildick-Smith, United Kingdom Jaroslaw Wójcik, Poland 15

EURO CTO CLUB MEMBERS PRESIDENT Alfredo R. Galassi Cannizzaro Hospital University of Catania, Catania, Italy PRESIDENT ELECT George Sianos AHEPA University Hospital Thessaloniki, Greece PAST PRESIDENT Gerald S. Werner Medizinische Klinik Klinikum Darmstadt, Darmstadt, Germany BOARD Carlo Di Mario Careggi University Hospital Florence, Italy BOARD Alexandre Avran Arnaud Tzanck Institut, Nice, France BOARD Evald Høj Christiansen Aarhus University Hospital, Skejby Aarhus, Denmark TREASURER Hans Bonnier University Hospital Brussels Brussels, Belgium FOUNDING MEMBERS Hans Bonnier, Belgium Heinz Joachim Büttner, Germany Carlo Di Mario, Italy Dariusz Dudek, Poland COORDINATOR MEMBERS Hans Bonnier, Belgium Nicolas Boudou, France Alexander Bufe, Germany Evald Høj Christiansen, Denmark Alfredo R. Galassi, Italy Valeri Gelev, Bulgaria Anthony Gershlick, United Kingdom Alfredo R. Galassi, Italy Nicolaus Reifart, Germany George Sianos, Greece Gerald S. Werner, Germany Tevfik Gürmen, Turkey Artis Kalnins, Lithuania Jacques Koolen, Netherlands Victoria Martin Yuste, Spain George Sianos, Greece Daniel Weilenmann, Switzerland Jaroslaw Wójcik, Poland 16 17

FULL MEMBERS Jürgen Arenz, Germany Alexandre Avran, France Hans Bonnier, Belgium Nicolas Boudou, France Leszek Bryniarski, Poland Alexander Bufe, Germany Heinz Joachim Büttner, Germany Mauro Carlino, Italy Evald Høj Christiansen, Denmark Joerg Dalibor, Germany Carlo Di Mario, Italy Dariusz Dudek, Poland Simon Elhadad, France Andrejs Erglis, Lithuania Javier Escaned, Spain Andrea Gagnor, Italy Alfredo R. Galassi, Italy Roberto Garbo, Italy Valeri Gelev, Bulgaria Anthony Gershlick, United Kingdom Omer Goktekin, Turkey Luca Grancini, Italy Tevfik Gürmen, Turkey Guy Heyndrickx, Belgium David Hildick-Smith, United Kingdom Karl Isaaz, France Artis Kalnins, Lithuania Jacques Koolen, Netherlands Harald Lapp, Germany Bernward Lauer, Germany Thierry Lefevre, France Aigar Lismanis, Lithuania Yves Louvard, France Victoria Martin Yuste, Spain Kambis Mashayekhi, Germany Markus Meyer-Gessner, Germany Michael Pieper, Switzerland Nicolaus Reifart, Germany Mark Rosenberg, Germany Gennaro Sardella, Italy Tim Schäufele, Germany Thomas Schmitz, Germany Antonio Serra, Spain George Sianos, Greece Horst Sievert, Germany James C. Spratt, United Kingdom Didier Tchetche, France Leif Thuesen, Denmark Imre Ungi, Hungary Daniel Weilenmann, Switzerland Gerald S. Werner, Germany Jaroslaw Wójcik, Poland ASSOCIATED MEMBERS Paul Das, United Kingdom Mauro De Benedictis, Italy Fabio Dell Avvocata, Italy Frits de Man, Netherlands Jo Dens, Belgium Laurent Drogoul, France Mohaned Egred, United Kingdom Mohammad El Garhy, Germany Mohamed El-Mawardy, Germany Martin Fanderl, Germany Daniele Forlani, Italy Sergey Furkalo, Ukraine Oliver Gaemperli, Switzerland Ali Reza Garachemani, Switzerland Salvatore Garibaldi, Italy Gabriele Luigi Gasparini, Italy Thomas Gehrig, Germany Robert Gerber, United Kingdom Alexander Ghanem, Germany Pietro Giudice, Italy Javier Goicolea, Spain Jan-Erik Gulker, Germany Dirk Hartel, Germany Karl-Eugen Hauptmann, Germany Dobri Hazarbasanov, Bulgaria Thomas Hovasse, France the stent behind the EuroCTO Trial Gerald S. Werner, MD PhD conclusion slide at EuroPCR 2017*...the results are relevant and demonstrate, that PCI of CTO improved the health status regarding angina frequency, physical limitations, and quality of life as compared to OMT, and improved the functional Class ASSOCIATED MEMBERS * source: https://media.pcronline.com/diapos/europcr2017/7103-20170518_0945_main_arena_werner_gerald_1111_(12614)/werner_gerald_20170518_0945_main_arena.pdf Ibrahim Akin, Germany Ralph Tomas Blank, Germany Alexander Alexandrov, Bulgaria Nenad Bozinovic, Serbia Iskandar Atmowihardjo, Germany Josko Bulum, Croatia Emanuele Barbato, Belgium Tushar Chatterjee, Switzerland Hakim Benamer, France Stephane Cook, Switzerland In Evidence Based Medicine We Trust! 18 19 BioMatrix is a trademark or registered trademark of Biosensors International Group, Ltd. Not available for sale in the United States and certain other countries. 2017 Biosensors International Group, Ltd. All rights reserved. 11803-000-EN - Rev.01

ASSOCIATED MEMBERS Dan Ioanes, Sweden Peiman Jamshidi, Switzerland Raban Jeger, Switzerland Risto Jussila, Finland Tito Kabir, United Kingdom Tomi Kaukonen, Finland Peter Kayaert, Belgium Paul Kelly, United Kingdom Neville Kukreja, United Kingdom Peep Laanmets, Estonia Alessio La Manna, Italy Eugenio La Scala, Italy Artur Lange, Germany Alexander Lauten, Germany Bertrand Ledermann, France Gregor Leibundgut, Switzerland Julien Lemoine, France Fabrice Leroy, France Maciej Lesiak, Poland Sébastien Levesque, France Raphy Levy, France Yuri Matchin, Russia Pietro Mazzarotto, Italy Massimo Medda, Italy Ian Menown, Ireland Gabriel Henrique Mesquita, Portugal Mohsen Mohandes, Spain Aris Moschovitis, Switzerland Claus-Heinrich Mueller, Germany Peter Mueller, Switzerland Göran Olivecrona, Sweden Jacopo Oreglia, Italy Sami Ozgul, Turkey Rosario Parisi, Italy Tomasz Pawlowski, Poland Stylianos Pixaras, Germany Rostyslav Prog, Germany Marek Radomski, Poland Sudhir Rathore, United Kingdom Gerd Ringwald, Germany Vincent Roolvink, Netherlands Christoph Rubens, Germany Mohammed Saad, Germany Meruzhan Saghatelyan, Armenia Joachim Schofer, Germany Ralph Schulze, Germany Gregory Sgueglia, Italy Fabio Sgura, Italy Imhad Sheiban, Italy Mohammad Sherif, Germany Georgios Sitafidis, Greece Nitin Sood, Germany Wojciech Stecko, Poland Sinisa Stojkovic, Serbia Julian Strange, United Kingdom Gabor Sutsch, Switzerland Aurel Toma, Germany Thor Trovik, Norway Carlo Tumscitz, Italy Beatriz Vaquerizo, Spain Zivile Valuckiene, Lithuania Ferdinando Varbella, Italy Marios Vlachojannis, Germany Constantin von zur Mühlen, Germany Piotr Wanczura, Poland Joachim Weber-Albers, Germany Inge Wijnbergen, Netherlands AFFILIATED MEMBERS Khaled Shokry, Egypt Khalid Tammam, Saudi Arabia HONORARY MEMBERS Antonio Colombo, Italy Jean Fajadet, France Martin Kaltenbach, Germany Chris Zambakides, South Africa Bernhard Meier, Switzerland Patrick Serruys, Netherlands 20 21

EURO CTO CLUB - STATISTICS Euro CTO Club members Industry Assembly 6 th European Live Summit on Retrograde CTO Revascularization Course Directors Alfredo R. Galassi, MD, FACC, FESC Thomas F. Luscher, MD, FACC, FESC George Sianos, MD, PhD, FESC April 28-29, 2017 - Zurich, Switzerland Course Vice Director & Coordinator Oliver Gaemperli, MD, FESC Euro CTO Club Members as of August 2017: 200 120 Industry Assembly 114 169 6 th 143 150 100 European Live Summit on 124 Retrograde 80 CTO Revascularization 100 52 60 April 28-29, 2017 - Zurich, Switzerland 50 29 33 38 43 52 55 61 40 21 13 13 20 3 se Directors 0 Course Vice Director & Coordinat 0 do R. Galassi Full, MD, FACC, Associated FESC Non-UE Oliver Full Gaemperli, Non-UE MD, FESC mas F. Luscher, MD, FACC, FESC Members Associate ge Sianos, MD, PhD, FESC Members Euro CTO Club membership 200 6 th European Live Summit on 138 Retrograde CTO Revascularization 124 150 100 April 28-29, 2017 - Zurich, 64 Switzerland 52 50 29 38 16 0 ourse Directors 182 Course Vice Director & Coordinator 2006 2008 2010 2012 2014 2015 2016 2017 Online Registry2008-2017 Online Registry 2008 2017 Full Members 3500 3000 2500 2000 1500 1000 Industry Assembly 6 th 2624 European 2577 Live Summit on1903 2000 Retrograde 2195 CTO Revascularization 1724 1303 3035 3024 3036 3216 1263 1500 April 28-29, 2017 - Zurich, 1762 Switzerland 1000 Associate Members Course Directors Course Vice Director & Coordinator 0 500 Alfredo R. Galassi, MD, FACC, FESC Oliver Gaemperli, MD, 2015 FESC 2016 2017 Thomas F. Luscher, MD, FACC, FESC 0 George Sianos, MD, PhD, FESC 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 500 1245 22 23

EURO CTO CLUB - STATISTICS Retrograde Approach 40 30 6 th European Live Summit 32 on 27,6 27,9 Retrograde CTO 24,9 Revascularization 0 ourse Directors fredo R. Galassi, MD, FACC, FESC 35,1 20 17,7 April 28-29, 2017 - Zurich, Switzerland 11,7 9,7 11,3 10 Course Vice Director & Coordinat 2008 2009 2010 2011 2012 2013 2014 2015 2016 Oliver Gaemperli, MD, FESC Antegrade/Retrograde Procedures Full Members 100% 80% 60% 40% Antegrade/Retrograde Procedures 10 11.5 10.5 14 Industry Assembly Associate Members 6 th 23 European 29 27.6 35.1 Live 32.8 Summit on 100% Retrograde CTO Revascularization 23.7 23.3 April 28-29, 2017 - Zurich, Switzerland 60% 90 88.5 89.5 86 77 40% 76.3 76.7 71 72.4 64.9 67.2 20% 20% Course Directors Course Vice Director 0% & Coordinator 2015 2016 Alfredo R. Galassi, MD, FACC, FESC Oliver Gaemperli, MD, FESC 0% Thomas F. Luscher, MD, FACC, FESC George 2008 Sianos, 2009 2010 MD, 2011 PhD, 2012 FESC 2013 2014 2015 2016 Antegrade Retrograde± Antegrade 80% Antegrade/Retrograde Operators Full Members 100% 80% 60% Industry Assembly Associate Members 6 th European Live Summit on 100% 50 Retrograde CTO Revascularization 69 71.4 80% 79.5 81.2 April 28-29, 85.4 83.4 2017 94.5 - Zurich, 92,8 Switzerland 60% 81.5 80 40% 40% 20% 50 19.5 20 20% Course Directors Course Vice Director 0% 31 28.6 & Coordinator 20.5 18.8 14.6 16.6 2015 2016 Alfredo R. Galassi, MD, FACC, FESC 5.5 Oliver 7,2 Gaemperli, MD, FESC 0% Thomas F. Luscher, MD, FACC, FESC George 2008 Sianos, 2009 2010 MD, 2011 PhD, 2012 FESC 2013 2014 2015 2016 Antegrade only Retrograde + Antegrade Angiographic Success Full Members 100 80 60 40 Angiographic Success Industry Assembly 85.5 86.5 88.1 87.6 87.8 90.3 87 89 89 Associate Members 6 th European Live Summit on 73.6 77.1 76.5 77.8 79.5 82.2 83.3 81.2 100 Retrograde 64.2 8.8 CTO Revascularization 91.3 80 78.1 81.2 April 28-29, 2017 - Zurich, Switzerland 60 40 20 20 Course Directors Course Vice Director & Coordinator 0 Alfredo R. Galassi, MD, FACC, FESC Oliver Gaemperli, MD, 2015 FESC2016 Thomas F. Luscher, MD, FACC, FESC 0 George Sianos, MD, PhD, FESC 2008 2009 2010 2011 2012 2013 2014 2015 2016 Antegrade Retrograde 24 25

We thank the following companies for their support! PLATINUM SPONSOR GENERAL INFORMATION 9th Experts Live September 15th 16th, 2017 Berlin, Germany Venue Hilton Berlin Mitte Mohrenstr. 30 10117 Berlin, Germany GOLD SPONSOR Language The official language of the congress is English. No simultaneous translation is available. Certificate of Attendance The Certificate of Attendance will be available on-site at the registration desk. The meeting is accredited by the European Board of Accreditation in Cardiology (EBAC). Registration fee Regular: 770,00 incl. VAT / per person Reduced rate for fellows: 350,00 incl. VAT / per person (physicians in education/training)* SILVER SPONSOR Registration fee includes - Admission to the Scientific Sessions - Catering during the breaks - Certificate of attendance Congress Dinner 65,00 incl. VAT / per person Friday, September 15th, 2017 Online registration: www.eurocto2017.com Contact Congress Organisation BRONZE SPONSOR Abiomed Acist/Bracco Bayer BBraun RenalGuard Solutions Siemens Stentys wikonect GmbH Hagenauer Straße 53 65203 Wiesbaden, Germany Phone: +49 (0) 611 204 809 14 Fax: +49 (0) 611 204 809 10 email: regina.lichte@wikonect.de www.wikonect.de 26 27

NOTES NOTES 28 29