IAS-sponsored Workshop on HDL 2007

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IAS-sponsored Workshop on HDL 2007 Co-sponsored by the Hellenic Society of Lipidology and Atherosclerosis and the Asian Pacific Society of Atherosclerosis and Vascular Diseases 9 12 October 2007 Santorini, Greece Meetings First 4/184 Main Street LILYDALE VIC 3140 Phone 61 3 9739 7697 Fax 61 3 9739 7076 Email athina@meetingsfirst.com.au

SUMMARY Conference IAS-sponsored Workshop on HDL 2007 Key Contacts Kerry-Anne Rye, John Chapman, John Kastelein and Philip Barter Dates 9 12 October 2007 Venue The Petros M Nomikos Conference Centre No. of Delegates Anticipated 120 Actual 181 DELEGATES A total of 181 delegates attended this workshop. Athina Patti and Jennifer Seabrook from Meetings First also attended the workshop. The workshop was advertised via email, brochures and via the Internet. The Meetings First mailing list comprised of Australian Atherosclerosis Society members, Asian Pacific Society of Atherosclerosis and Vascular Diseases members and the 2004 HDL Workshop participants. Emails were also sent to everyone on the International Atherosclerosis Society mailing list. The Hellenic Society of Lipidology and Atherosclerosis also advertised the workshop directly to their members. All those on the Meetings First mailing list and the International Atherosclerosis Society mailing list received email reminders of the conference, early bird registration deadline and close of abstract submissions. Brochures were also distributed at the following three meetings: - European Atherosclerosis Society Congress 2007, 10 13 June 2007, Helsinki, Finland - 10th Annual Scientific Forum of the Southeast Lipid Association, 3 5 August 2007, USA - H.E.A.R.T UK 21st Annual Medical & Scientific Meeting, 27 29 June 2007, Edinburgh, UK The workshop was also advertised on the following websites: - Meetings First - International Atherosclerosis Society - Australian Atherosclerosis Society - Asian Pacific Society of Atherosclerosis and Vascular Diseases Michael Gibbs also arranged advertising of the meeting in the following journals: DVDRes, BJC and BJDVD. Meetings First designed these advertisements. All announcements and the website were designed in-house by Meetings First. Registrations from Number Registrations from Number Armenia 1 Italy 19 Australia 4 Japan 8 Austria 4 Korea 6 Belgium 1 Netherlands 16 Brazil 1 New Zealand 1 Canada 8 Russia 1 Czech Republic 2 Serbia 2 Egypt 1 South Korea 1 Finland 3 Spain 7 France 7 Sri Lanka 1 Georgia 2 Sweden 2 Germany 1 Switzerland 10 Greece 8 Taiwan 1 Hong Kong 1 United kingdom 6 Indonesia 2 USA 53 Israel 1 Total 181

An evaluation form was printed onsite and distributed to delegates on the final day of the workshop. Responses were very positive, with most delegates enjoying the workshop. VENUE In April 2006, Kerry-Anne Rye and Jennifer Seabrook completed a site inspection, which included Crete, Santorini, Rhodes and Loutraki on the mainland. It was decided that the meeting would be held in Santorini at the Petros M Nomikos Conference Centre, as it was the most appropriate. A registration desk was set up in the foyer of the Conference Centre, just outside the lecture theatre. Poster boards were set up in the just outside of the foyer, in a covered outdoor tunnel. The poster boards were a permanent fixture of the Conference Centre and were at no additional cost. Catering was also in this area and delegates could be seated during the breaks either indoors or in the outdoor courtyard. The space worked well. However, as quite a number of delegate s posters were larger than the recommended size, some posters had to be sticky taped to walls, etc. The meeting room was a good size for the number of people that attended the meeting. Delegates were also able to sit upstairs in the balcony area. As poster boards, audiovisual equipment and the technician were provided by the venue at no extra charge, this assisted in keeping costs low. MEETING The meeting commenced at 2.00pm on Tuesday 9 October 2007 and concluded at 12.15pm on Friday 12 October 2007. Delegates were given a free afternoon on the Thursday. The program consisted of the following topics and sessions: - Cholesterol Efflux/Reverse Cholesterol Transport-Mechanisms and Regulation - HDL Structure and Function - HDL Apolipoproteins - HDL and the Prevention of Atherosclerosis: Animal Studies - Other Functions of HDL - Low HDL States: Metabolic Causes - Therapeutic Approaches for Raising HDL - Low HDL States: Genetic Causes - Basic Research Moderated Poster Session - Basic Research Poster Session (during morning tea) - Clinical Research Moderated Poster Session - Clinical Research Poster Session (during morning tea) - Young Investigator Finalists Poster Session (during morning tea) - Young Investigator Awards Invited speakers were: - Dr Bryan Brewer, Cardiovascular Research Institute, USA - Dr Laura Calabresi, University of Milano, Italy - Professor John Chapman, INSERM, France - Professor Linda Curtiss, The Scripps Research Institute, USA - Professor Sean Davidson, University of Cincinnati, USA - Dr Peter Edwards, University of California Los Angeles, USA - Professor John Griffin, The Scripps Research Institute, USA - Professor Michael Hayden, Centre for Molecular Medicine and Therapeutics, Canada - Professor Jay Heinecke, University of Washington, USA - Professor Wendy Jessup, University of New South Wales, Australia - Professor John Kastelein, Academic Medical Center, Netherlands - Dr Anatol Kontush, National Institute of Health and Medical Research, France - Dr Jan Albert Kuivenhoven, University of Amsterdam, Netherlands - Dr John Paolini, Merck Research Laboratories, USA - Professor Michael Phillips, University of Pennsylvania, USA - Professor George Rothblat, Children s Hospital of Philadelphia, USA

- Professor Kerry-Anne Rye, The Heart Research Institute, Australia - Professor Ernst Schaefer, Tufts University, USA - Professor Jere Segrest, University of Alabama, USA - Professor Philip Shaul, UT Southwestern Medical Center at Dallas, USA - Professor Mary Sorci-Thomas, Wake Forest University Health Sciences, USA - Professor Bart Staels, Institut Pasteur de Lille, France - Professor Alan Tall, Columbia University, USA - Professor Marja-Riitta Taskinen, Helsinki University Hospital, Finland - Dr Miranda van Eck, Leiden/Amsterdam Center for Drug Research, Netherlands - Professor Luc van Gaal, Antwerp University Hospital, Belgium - Professor Gerald Watts, University of Western Australia, Australia - Professor Karl Weisgraber, University of California, USA - Dr Norman Wong, Resverlogix Corporation, Canada - Professor Shinji Yokoyama, Nagoya City University, Japan - Professor Vassilis Zannis, Boston University, USA All speakers with the exception of Dr Norman Wong received complimentary registration and attendance to social functions, an amount towards travel and 4 nights accommodation. Professor Christian Ehnholm, National Public Health Institute, Finland was an invited chairperson and also received the same remuneration as the speakers did. Professor Ehnholm was the only invited chairperson. All other chairpersons were the invited speakers. ABSTRACTS A total of 107 abstracts were received. This includes 31 abstracts submitted by speakers. As 17 of these abstracts were withdrawn, a total of 90 abstracts were included in the meeting, either as oral presentations by invited speakers or as posters by registered delegates. Distribution of presented abstracts (including speakers) is as follows: Country Number of abstracts submitted Australia 3 Austria 2 Belgium 1 Canada 7 Czech Republic 1 Finland 1 France 4 Georgia 1 Greece 6 Hong Kong 2 Indonesia 2 Italy 8 Japan 4 Korea 5 Netherlands 13 Russia 1 Serbia 2 Spain 2 Sweden 2 United Kingdom 2 USA 21 Total 90 Abstract reviewers were Professor Sean Davidson, Dr Jan Albert Kuivenhoven and Professor Gerald Watts. Once these three reviewers scored the abstracts, Professor Franz Rinninger and Dr Gordon Francis were asked to rank the Clinical Research Posters and Professor Vassilis Zannis and Associate Professor Antonis Zampelas were asked to rank the Basic Research posters for placement in the Moderated Poster Sessions.

AWARDS Award judges were Professor Sean Davidson, Dr Jan Albert Kuivenhoven and Professor Gerald Watts. The following people were Young Investigator Award finalists: - Willeke de Haan, Leiden University Medical Center, Netherlands - Elda Favari, University of Parma, Italy - Alessandro Guerini Rocco, Universita' degli Studi di Milano, Italy - Illiana Meurs, LACDR, Leiden University, Netherlands - Claudine Neyen, Sir William Dunn School of Pathology, United Kingdom - Spencer Proctor, University of Alberta, Canada - Efstathia Thymiakou, University of Crete, Greece - Reeni van Rijn-Hildebrand, Leiden/Amsterdam Center for Drug Research, Netherlands - Carlos Vrins, Academic Medical Center, Netherlands - Thomas Weichhart, Medical University of Vienna, Austria - Ilaria Zanotti, University of Parma, Italy The winners were as follows: - Winner: Iiaria Zanotti - Runner-up: Thomas Weichart - Honourable mention: Carols Vrins SOCIAL FUNCTIONS Welcome Dinner, sponsored by sanofi aventis The Welcome Dinner was held on Tuesday 9 October 2007 and was originally going to be held only at the Archipelagos Restaurant, but due to the large increase in numbers, a decision was made to hold the function at an additional two restaurants. These restaurants were Sphinx Restaurant (next door) and Calderimi Restaurant (a few doors down). The decision to hold the dinner in 3 locations was due to the fact that there were no restaurants located near the hotels that could accommodate the number of attendees. As it was the first night in Santorini and most people travelled a long way, the Organising Committee wanted to give delegates the opportunity to walk back to their hotel at any stage of the night. There were 180 delegates and partners in attendance. VIP Dinner The VIP Dinner was held at Archipelagos Restaurant on Wednesday 10 October 2007. All speakers and partners were invited to attend this function. Prior to the meeting, 53 people confirmed their attendance; therefore, dinner was paid for 53 people. Unfortunately, at the meeting, quite a number of people said that they no longer wanted to attend, and only about 20 people attended this function. Conference Dinner, sponsored by F Hoffmann-La Roche The Conference Dinner was held at Pyrgos Restaurant on Thursday 11 October 2007. This restaurant was not within walking distance to the hotels, so all delegates needed to take the buses provided. There were 177 delegates and partners in attendance. All enjoyed this night with entertainment provided by a live Greek music band and folklore dancers. TRANSFERS Bus transfers were arranged to take delegates to and from the Conference Centre each day. The only hotel that did not have this service was the Hotel Santorini Palace, as it was within walking distance. Bus transfers were also arranged to take function attendees to and from the venues at each function.

SPONSORS A Sponsorship Prospectus was designed and distributed within the pharmaceutical industry by John Chapman, John Kastelein, Kerry-Anne Rye, Philip Barter and Michael Gibbs. Meetings First kept in close contact with all sponsors in the months approaching the meeting to make arrangements on their behalf. ORGANISATION We were delighted to assist with the organisation of this meeting. It has been an absolute pleasure working with the Organising Committee. Meetings First staff spent 572 hours working on this meeting. COMMENTS We would recommend the following when organising the next HDL Workshop: - Do not hold a VIP dinner, as most people did not attend or make it a spontaneous event. Thank you for the opportunity to work with you on this project. We trust you agree that the meeting was indeed a success.