RETINOBLASTOMA: AN INTERNATIONAL UPDATE

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3 rd INTERNATIONAL MEETING RETINOBLASTOMA: AN INTERNATIONAL UPDATE INTERNATIONAL FACULTY F. Doz Paris G. Chantada Buenos Aires F. Munier Lausanne September 7th - 8th 2018 Auditorium S. Paolo Ospedale Pediatrico Bambino Gesù V.le F. Baldelli, 38-00146 Roma

CON IL PATROCINIO DI:

COURSE DIRECTORS SCIENTIFIC SECRETARIAT Roberta Ardia Angela Di Giannatale Rosa Parrilla Ida Russo Paola Valente FACULTY Raffaele COZZA Martina ANGI (Italy, Milan) Astrit BECI (Shkodra - Albania) Luca BUZZONETTI (Italy - Rome) Guillermo CHANTADA (Buenos Aires - Argentine) Raffaele COZZA (Italy - Rome) Guendalina DALMASSO (Italy - Rome) Pim DE GRAAF (Netherlands - Amsterdam) Angela DI GIANNATALE (Italy - Rome) Francois DOZ (France - Paris) Angela GALLO (Italy - Rome) Paolo GALLUZZI (Italy - Siena) Theodora HADJISTILIANOU (Italy - Siena) Vesna ILIC (Serbia - Belgrade) Monica KONIG KAKS (Germany) Franco LOCATELLI (Italy - Rome) Dietmar LOHMANN (Germany - Essen) Livia LUMBROSO LE ROUIC (Paris, France) Silvia MIGNANI (Italy - Rome) Antonino ROMANZO Ophthalmology department, Rome roberta.ardia@opbg.net Hematology and Oncology department, Rome angela.digiannatale@opbg.net Ophthalmology department, Rome rosa.parrilla@opbg.net Hematology and Oncology department, Rome ida.russo@opbg.net Ophthalmology department, Rome paola.valente@opbg.net Alessandra MODUGNO (Italy - Rome) Annette MOLL (Netherlands - Amsterdam) Ángel MONTERO CARCABOSO (Spain - Barcelona) Francis MUNIER (Switzerland - Lausanne) Isabella NICOLAI (Italy - Rome) Antonio NOVELLI (Italy - Rome) Maya Beck POPOVIC (Switzerland - Lausanne) François RADVANYI (France - Paris) Francesco RANDISI (Italy - Rome) Dejan M. RASIC (Serbia - Belgrade) Massimo ROLLO (Italy - Rome) Antonino ROMANZO (Italy - Rome) Ida RUSSO (Italy - Rome) Marija Pudrlja SLOVIC (Serbia - Belgrade) Maria Valentina SOFIA (Italy - Rome) Paola VALENTE (Italy - Rome) Vicktoria VISHNEVSKIA-DAI (Israel - Tel Aviv) SCIENTIFIC PROGRAM September 7th Friday 2018 08.00 Registration and Welcome Breakfast 08.15 Opening greetings Luca Buzzonetti, Franco Locatelli 08.30 GENETICS OF RETINOBLASTOMA 15 minutes talk Chairmen: Francis Munier, Antonino Romanzo Translating genetic knowledge into benefits for patients with retinoblastoma and their families Dietmar Lohmann The molecular genetics of retinoblastoma: the experience of Bambino Gesù Children s Hospital Novelli Antonio - Sofia Maria Valentina 10.00 Coffee break 10.30 MOLECULAR BIOLOGY 15 minutes talk Chairmen: Francois Doz, Angela Di Giannatale Targeting the dysfunctional Rb pathway in retinoblastoma with the oncolytic adenovirus VCN-01 Ángel Montero Carcaboso Liquid biopsy: exploring new biomarkers in retinoblastoma Angela Di Giannatale Molecular heterogeneity of retinoblastoma François Radvanyi RNA modifications in retinoblastoma Angela Gallo 12.00 CONSERVATIVE TREATMENTS IN RETINOBLASTOMA: THE CURRENT EUROPEAN PROTOCOLS - I SESSIONE 15 minutes talk Chairmen: Raffaele Cozza, Francois Doz 13:00 Lunch Oncology treatment: Francois Doz Guillermo Chantada Maya Beck Popovick Ida Russo

14.00 CONSERVATIVE TREATMENTS IN RETINOBLASTOMA: THE CURRENT EUROPEAN PROTOCOLS - II SESSIONE 10 minutes talk Chairman: Antonino Romanzo, Francis Munier Ophthalmology treatment in Europe: Francis Munier, Livia Lumbroso-Le Rouic, Paola Valente Management of children with retinoblastoma in Israel (Tel Aviv) Vishnevskia-Dai Vicktoria Management of children with Retinoblastoma in Serbia Vesna Ilic, Marija Pudrlja Slovic Retinoblastoma in Serbia - current trends, realities and practices Dejan M. Rasic 20 Years of experience in Retinoblastoma Management in Albania Astrit Beci A roundtable discussion: Conservative treatments: time to think about a common EurBG protocol - 40 minutes talk : Francois Doz, Guillermo Chantada, Francis Munier, Theodora Hadjistilianou, Maya Beck Popovic, Raffaele Cozza, Antonino Romanzo, Martina Angi, Vicktoria Vishnevskia-Dai, Livia Lumbroso-Le Rouic 16.00 Coffee break 16.30 How could EurBG help developing countries? A roundtable Introduction: Guillermo Chantada, Monica Konig Kaks : Mariella Enoc, Flaminia Giovannelli, Massimiliano Raponi Francois Doz, Francis Munier, Raffaele Cozza, Antonino Romanzo, Theodora Hadjistilianou, Vicktoria Vishnevskia-Dai, Livia Lumbroso-Le Rouic 17.30-18.30 Parental Group RETINOSTOP - France AILR - Italy KAKS - Germany September 8th Saturday 2018 08.30 QUALITY OF LIFE 15 minutes talk Chairmen: Annette Moll, Antonino Romanzo, Guendalina Dalmasso 11.00 Coffee break Psychosocial care and research for retinoblastoma patients in the Netherlands Annette Moll Psychological support for parents and children with retinoblastoma Silvia Mignani Outpatient Area in Santa Marinella Isabella Nicolai Orbital surgery Antonino Romanzo Protesis and aesthetic rehabilitation Alessandra Modugno 11.30 NEUROIMAGING 15 minutes talk Chairmen: Massimo Rollo, Paolo Galluzzi 12.30 Test Orbital examination MR techniques Francesco Randisi (Italy - Rome) MRI of Retinoblastoma Pim De Graaf (Netherlands Amsterdam) MRI of lesions simulating Retinoblastoma Paolo Galluzzi (Italy - Rome) 13.00 Conclusions Luca Buzzonetti, Franco Locatelli

SPONSOR: NOTE

NOTE

This meeting aims to enhance the clinical and preclinical knowledge of Retinoblastoma through advanced discussion amongst the experts in this field. In particular we propose an update on molecular biology, diagnosis, conservative and non conservative Retinoblastoma management, radiological guidelines, Pediatric Ocular Oncology outpatients department, Bambino Gesù Pediatric Hospital, Santa Marinella late effects and quality of life. This initiative is scientifically supported by the European Retinoblastoma Group «EURbG», in which the Bambino Gesù Pediatric hospital is actively involved as a member. Since its first foundation in 2015, «EURbG» project aimed to create a network among experts in Retinoblastoma care from all major european centers, as well as providing access to reliable, consistent information and assistance to patients and families affected by the disease. We hope that this meeting will be an ideal venue for discussion amongst all participants and will promote international collaboration. Looking forward to meeting everyone in Rome next year. GENERAL INFORMATION DATE AND VENUE: 7-8 September 2018 Auditorium S. Paolo - Ospedale Pediatrico Bambino Gesù, P.zza S. Onofrio, 4-00165 Roma REGISTRATION: http://www.formazione.ospedalebambinogesu.it/ Only for foreign participants: please write an e-mail to congressi@opbg.net and we will send the registration form. Only 150 participants will be accepted. Simultaneous Translation will be provided. EDUCAZIONE CONTINUA IN MEDICINA - E.C.M. The Course will assign 7 ECM credits to the following categories of Italian partecipants: Medico Chirurgo (Ematologia, Genetica Medica, Oncologia, Pediatria, Pediatria- Pediatri Di Libera Scelta, Radioterapia, Oftalmologia, Anestesia e Rianimazione, Laboratorio Di Genetica Medica, Neuroradiologia, Radiodiagnostica, Psicoterapia); Biologo; Fisico (Fisica Sanitaria); Infermiere; Infermiere Pediatrico; Ortottista/Assistente in Oftalmologia; Psicologo/Psicoterapeuta; Tecnico Sanitario Radiologia Medica. ORGANIZING SECRETARIAT Servizio Eventi Formativi ECM - Ospedale Pediatrico Bambino Gesù Piazza S. Onofrio, 4-00165 Roma - Tel: 06-6859.4864/2290/2411/3770/4758/3154 Fax: 06/6859.2443 - E-mail: congressi@opbg.net - www.ospedalebambinogesu.it